Author: Ge Hui

  As more and more people are infected with the Omicron virus, the demand for the antipyretic drug ibuprofen has surged, making it one of the most difficult to buy anti-epidemic materials, but the situation of "one medicine is hard to find" is being eased.

  my country has a huge production capacity of ibuprofen. Recently, Hubei, Shandong, Zhejiang and other places are increasing their supply guarantees to produce ibuprofen and put it on the market.

Among them, Wuhan started to release 3 million tablets of ibuprofen every day for a week starting from December 17. Jinan announced that 1.1 million tablets of ibuprofen have been released, and Zhejiang said that the daily production of ibuprofen granules has reached 40,000 boxes. , Yichang Renfu said that it does not stop the machine, and can produce 3,800 ibuprofen tablets per minute. Hefei, Nanjing, Fuzhou and other places are also distributing anti-epidemic "health packs" containing ibuprofen and other drugs.

Three million tablets of ibuprofen are dispensed daily in Wuhan

  On the evening of December 17, the "Hubei Release" official announced that "3 million tablets of ibuprofen will be released from today!".

According to the news, starting from December 17, China Resources Hubei Pharmaceutical Co., Ltd. "distributed 3 million tablets of ibuprofen to Wuhan area every day for a week, 80% of which were distributed to medical institutions and 20% to retail pharmacies. One week later According to market demand, the company will adjust the plan to continue to ensure the supply of Wuhan, and will continue to increase the supply of four types of drugs, including Lianhua Qingwen, to the Wuhan market."

  According to the news released by Hubei, “according to the public’s demand for therapeutic drugs, China Resources Hubei Pharmaceutical Co., Ltd. has successively established contacts with many well-known pharmaceutical companies such as China Resources Sanjiu Pharmaceutical, Yiling Pharmaceutical, Wutai Pharmaceutical Group, and Taiji Group. Carry out emergency procurement, establish a green channel for payment, simplify the approval process, and speed up the release of drugs as soon as possible. Since December, a total of 65,000 pieces of 4 types of drugs have been released."

  Also in Hubei, according to the "Yichang release" news, "Yichang Renfu Pharmaceutical has expanded the existing product batches to more than double, and can produce 3,800 ibuprofen tablets per minute. Yichang Renfu Pharmaceutical's Yuanan oral preparations In the production workshop, in addition to ibuprofen tablets, there are also three kinds of medicines, such as acetaminophen tablets, compound acetaminophen capsules, and pholcodine syrup. In addition, Renfu Pharmaceutical is also planning to add 30 small packaging cloths Luofen, "On the basis of the original packaging of 100 tablets per bottle, a small package of 30 tablets per bottle is added.


  Not only has it stepped up efforts in production, Hubei Province announced this month to lower the price of ibuprofen. The website of the Hubei Provincial Medical Security Bureau issued a notice to adjust 21 products including ibuprofen suspension and Bairui granules from December 20. Drug prices linked to the Internet.

Among them, the ibuprofen suspension (100ml:2g) produced by Xiangyu Pharmaceutical was lowered from 15.53 yuan to 13.16 yuan, a price reduction of 15.26%.

  On December 18, the Zhejiang Provincial Government Information Office held a press conference on the prevention and control of the new crown epidemic. At the meeting, it stated that it would focus on strengthening the production, storage and supply of anti-epidemic materials such as anti-virus, heat-clearing and detoxifying Chinese patent medicines, and antigen reagents, and promote the development of relevant enterprises. Full horsepower, increase production capacity, and increase the production and supply of drugs. The daily output of ibuprofen granules has reached 40,000 boxes, and the production capacity of related key drugs is expected to be further increased before the end of the month.

In order to achieve accurate distribution of materials, the provincial economic and information department dynamically monitors the shortage of medical materials in the market, dispatches the production of key enterprises and key varieties, and guarantees the needs of medical institutions in the province, especially.

  According to the "New Yellow River" news, in response to the public's complaints about the shortage of antipyretics, on December 16, the Jinan City Headquarters medical supplies support team urgently deployed 500,000 tablets of ibuprofen to support key links such as grassroots clinics and pharmacies. All served.

On December 17, 600,000 tablets of ibuprofen will continue to be deployed to ease the pressure on the city's demand for medicines.

  According to the news, at present, the "four types of drugs" manufacturers in Jinan City include 8 companies including Freda Pharmaceutical, Hongjitang Pharmaceutical, Qilu Pharmaceutical, and Shuanghe Limin Pharmaceutical, with a total of 42 varieties. Among them, antipyretic drugs A total of 21 kinds of medicines, such as Compound Amphenamine Capsules, cough medicine Ambroxol Hydrochloride Injection, antibiotic medicine Cefixime Capsules, and antiviral medicine Fangfengtongsheng Pills, are being produced at full production capacity with sufficient inventory reserves.

  "Health packs" containing ibuprofen distributed in many places

  On December 8, the "Hefei Municipal People's Government issued" that Hefei is stockpiling "health packs" in an orderly manner, including 2 boxes of antiviral drug Lianhua Qingwen capsules and 1 box of antipyretic ibuprofen sustained-release capsules in the regular version for adults. box, 1 thermometer, 2 N95 masks, 2 bottles of 100ml alcohol spray.

The children's version includes 1 box of Lianhua Qingwen granules, 1 box of ibuprofen drops, 1 thermometer, 2 N95 masks, and 2 bottles of 100ml alcohol spray.

On December 11, "Hefei released" news that all counties (cities, districts) in Hefei stockpiled "health packs" according to the minimum requirement of 200,000 copies, and gave them free of charge to asymptomatic and mildly infected persons treated at home.

  Fuzhou is also preparing to release anti-epidemic drugs containing ibuprofen.

On December 11, according to Fuzhou News Network, Fuzhou, Fujian Province is orderly stocking up with loving "health packs".

The first batch of 10,000 "health packs" will be given free of charge to citizens and friends who have been assessed to need home treatment.

It is understood that it includes 1 box of Lianhua Qingwen granules, 1 box of ibuprofen sustained-release capsules, 1 thermometer, 10 N95 masks, and a box of antigen detection reagents.

  The official account of the Propaganda Department of Jianye District, Nanjing City "Jianye Broadcasting" stated that starting from December 8, Jianye District will issue "health care packages" to those who are positive for home isolation, including essential medicines, medical treatment guidelines, masks, thermometers, and antigen detection. Reagents etc.

There are medicines such as Shufeng Jiedu Capsules, Ibuprofen Sustained Release Capsules, Compound Pseudoephedrine Hydrochloride Sustained Release Capsules, Ambroxol Hydrochloride Oral Solution etc. in the Youxin package.

Guaranteed supply of anti-epidemic medicines

  On December 7, the Joint Prevention and Control Mechanism of the State Council released guidelines for the home treatment of patients with COVID-19 infection and a reference to commonly used medicines, listing commonly used medicines based on seven symptoms including fever, dry throat, and cough and expectoration. Symptomatic drugs are included.

In the folk drug stockpiling list, ibuprofen is highly regarded as a must-have star drug.

In reality, pharmacies in many places are out of stock of ibuprofen.

  However, my country has a huge production capacity of ibuprofen. According to a previous report by China Business News, the main domestic suppliers of ibuprofen raw materials are Xinhua Pharmaceutical (000756.SZ) and Hendy Pharmaceutical (301211.SZ).

Among them, Xinhua Pharmaceutical is the largest manufacturer of ibuprofen raw materials in the world, and Hubei Baike Hendy Pharmaceutical Co., Ltd. is the largest supplier of non-steroidal anti-inflammatory drug ibuprofen in China and the second in the world.

  Judging from the financial report data disclosed by ibuprofen raw material manufacturers, the amount of raw materials that relevant manufacturers can produce is quite large.

Take Hendy Pharmaceuticals as an example. In 2020, the company's sales of ibuprofen raw materials will reach 3732.32 tons.

In terms of the common 0.3g specification, 1 ton of ibuprofen API can produce 3,333,300 ibuprofen preparations, and 3,000 tons of ibuprofen API can produce 10 billion ibuprofen preparations.

In addition, the company is also expanding the production of ibuprofen raw materials, and one of its IPO fundraising projects is to increase the annual production of 5,000 tons of ibuprofen raw materials.

  According to news from the official website of Xinhua Pharmaceutical, as an important manufacturer of antipyretic and analgesic drugs in my country, Xinhua Pharmaceutical has formulated a plan to increase production and expand capacity for "one drug, one policy" for key drugs such as ibuprofen, and try every means to tap existing production capacity to further improve product quality and yield.

Hualu Group will focus on fully supporting Xinhua Pharmaceutical to expand production capacity to ensure market supply, ensure that the production capacity of key drugs such as ibuprofen is doubled by the end of December, and provide more affordable and reliable medicines for the common people.

  Yichang Renfu in Hubei said that the company set up a special supply guarantee team for the production of anti-epidemic drugs in a timely manner, and took the form of non-stop work to ensure the production of anti-epidemic drugs.

Other medicines produced by the company for the relief of symptoms of the new coronavirus include acetaminophen tablets, compound acetaminophen capsules, compound phalcodine syrup, etc.

The products produced in the early stage have been put into several local chain drugstores one after another, and will continue to be supplied in the near future.

Zhou Zongshan, director of the Yichang Branch of the Hubei Provincial Drug Administration, said, "We will spare no effort to provide strong support. Special cases are specially handled for emergency approval. Enterprises take the time to prepare application materials.

Strengthen the supervision of epidemic prevention materials

  In addition to increasing production and delivery, regulatory authorities in various places are also stepping up their efforts to supervise and enforce prices of epidemic-related materials.

  In response to the abnormal price fluctuations in the market for epidemic-related materials such as Lianhua Qingwen, ibuprofen, antigen detection reagents, and N95 masks, the Zhejiang Provincial Market Supervision and Administration Bureau quickly deployed all regions to increase epidemic-related medical drugs (including traditional Chinese medicinal materials) and antigens. The price supervision and law enforcement of three types of epidemic-related materials, testing reagents and protective equipment (masks, etc.).

On December 16, the Bureau announced the first batch of typical cases of price gouging of epidemic-related materials.

Among them, in the process of selling ibuprofen sustained-release capsules, a pharmacy in Shaoxing City forced tie-in sales of other products, which in a disguised form greatly increased the price of the product. It was suspected of constituting an illegal act of driving up prices. The Keqiao District Market Supervision Bureau filed a case on December 12. The investigation will make an administrative penalty decision in the near future.

  In Jiangsu, on December 13, the Haimen District Market Supervision Bureau of Nantong City conducted a law enforcement inspection on the Xin* Pharmacy in Haimen District based on the clues reported.

By checking the sales flow and sales receipts of the parties involved, it was found that the pharmacy was forced to sell about 200 yuan per person of antibiotics, Radix Radix and other drugs when selling ibuprofen, which was suspected of constituting an illegal act of driving up prices.

At present, the Haimen District Market Supervision Bureau of Nantong City has filed a case for investigation and will make an administrative penalty decision in the near future.