Anna Anvegård, 24, has scored nine goals in 24 international matches.
There are now fears that the tenth goal may have to wait longer than hoped.
The 24-year-old has been re-diagnosed with a concussion, her third in the space of a year.
World Cup qualifiers next month
The Everton club team now confirms that she will be out for a longer period.
- Anna has suffered a concussion and we are not sure when she will return.
So she will be gone indefinitely, says head coach Chris Robertson at a press conference.
Sweden will play World Cup qualifiers against Georgia in Gori on April 7 and then host Ireland at home in Gothenburg on April 12.