Sevilla got off to a dream start in the return encounter at home. 1-0 came in the first minute when Harry Maguire was put under pressure just outside his own penalty area, struck with the ball and Youssef En Nesyri took over and placed it.
"It's their own fault. David De Gea plays an obvious pass to Maguire and three Sevilla players stab straight away. It's slow, predictable and it was punished," said BBC pundit Rob Green.
Right at the start of the second half, Sevilla were able to extend to 2-0 after a "header" on a corner from center back Loic Bade. Rather, the ball hit the Frenchman's shoulder and went in a perfect arc over David De Gea, via the crossbar, and in.
'A deplorable goal'
Manchester United, with Victor Nilsson Lindelof from the start, tried to pull themselves up. Marcus Rashford was substituted after the half-time break, but the danger did not materialise. Sevilla defended their lead comfortably and were instead able to make it 3-0 after another hefty blunder.
A real high ball from Sevilla ended up at David De Gea who tried to cushion it down, but he missed the reception entirely. Then En Nesyri was there to lift the nail into the coffin and secure Sevilla's victory in the quarter-finals.
"It's a sad goal that ends a miserable night for Manchester United. A new gift, says Rob Green.