"At 04:40 (00:40 Moscow time) in the Kargatsky district on the P-254 Irtysh highway, the driver, driving a Renault Sandero, drove into a lane for oncoming traffic, where he collided with a KamAZ car with a trailer," RIA Novosti quotes Stradymov.
As a result of the collision, the driver and two passengers of the car, including a small child, were killed on the spot.
Investigators establish the causes and circumstances of the incident.
Earlier in Samara, a passenger car crashed into a standing ambulance, as a result of the accident, three people were killed and two were injured.