Research has shown that the Corona 19 virus (SARS-CoV-2), which caused Corona 19's global pandemic (pandemic), acquired the ability to infect the human body during bats and pangolins.

The joint research team led by Professor Dunggao Medical Center of Duke University in the United States on the 1st in the international journal 'Science Advances' genetic analysis showed that the closest to the corona19 virus is the bat coronavirus, but its ability to penetrate the human body is an important gene with the coronavirus It is said to have been obtained by exchanging pieces.

It has been known since the early days of the Corona 19 epidemic that the Corona 19 virus is genetically most similar to the bat Corona virus.

However, a clear path has not been elucidated, including claims that the virus has since spread from pangolin to humans.

The team explained that the innate coronavirus, which is inherent in panacea, cannot cause pandemics directly in humans, but the spike protein on the surface of the virus has a receptor binding site for binding to human cells.

When this binding site of the celestial coronavirus was transmitted to the bat coronavirus, a new virus was created that easily binds the surface proteins of many angiotensin converting enzymes 2 (ACE2) to human respiratory and intestinal epithelial cells, endothelial cells, and kidney cells. .

Researchers say that the bat coronavirus is genetically closest to the corona19 virus, but that the binding site of this coronavirus is very different, making it impossible to efficiently infect human cells. He explained that it appeared to be a corona19 virus.

"The original SARS (severe acute respiratory syndrome) that has been transmitted from bats to musk cats to humans, or the MERS (Middle East Respiratory Syndrome) virus, which has been transmitted from bats to humans through camels," Coringa said. 19 Viruses have also become genetically evolving and have the ability to infect humans. ”

Researchers say the virus can jump between species because it acquires the ability to bind to host cells through genetic changes on its own. Tracking the evolutionary pathways of these viruses will suppress the pandemic caused by these viruses in the future and prevent vaccines. It will help to develop.