Vaccination against HPV is one of the key means to eliminate cervical cancer. In January 2024, the State Food and Drug Administration officially approved the import of the nine-valent human papillomavirus vaccine (commonly known as the "nine-valent HPV vaccine") to add 2 doses of immunization program for women aged 9-14 years old, that is, 2 doses of full vaccination. The interval between the first dose and the second dose is 6-12 months.
The updated immunization schedule is: For women aged 9-14, the imported nine-valent HPV vaccine can choose a 2-dose immunization schedule, that is, 1 dose in 0 and 6 months, with an interval of not less than 5 months. You can also choose 3-dose immunization schedule; women aged 15-45 years can still only choose the 3-dose immunization schedule. From the previous three injections to two injections, this adjustment is undoubtedly good news for girls of appropriate age who want to be vaccinated, because the two-dose vaccination procedure simplifies the vaccination process and reduces the cost of vaccination. What is the protective effect of the adjusted 2-dose vaccination? Is there any difference from 3 doses? Jiangsu CDC recently conducted an authoritative Q&A.
Question 1: My child is young now, is it necessary to get HPV vaccine?
The top three high-risk HPV subtypes that Chinese women are most susceptible to are: HPV16, HPV52, and HPV58. The HPV infection rate shows a "bimodal" distribution by age, with the first peak of infection in "17-24 years old" and the second peak in "40-44 years old". Completing HPV vaccination for teenage girls before the age of 15 is one of the keys to eliminating cervical cancer.
Question 2: After girls aged 9-14 have been vaccinated with 1 or 2 doses of 9-price vaccine, how should they adjust the vaccination schedule?
Girls aged 9-14 can take a 2-dose or 3-dose vaccination plan.
Those who have been vaccinated with 1 dose: You can choose the 2-dose or 3-dose vaccination procedure. Please refer to the imported nine-price instructions.
Those who have received 2 doses: If the interval between the second dose and the first dose is less than 5 months, the third dose should be vaccinated; if the interval between the second dose and the first dose is not less than 5 months, no vaccination is required Dose 3.
Question 3: Can females aged 9-14 years old only choose the 2-dose immunization schedule of the nine-valent HPV vaccine? How safe and effective is it?
According to the recommendations of the new nine-valent HPV vaccination instructions, women aged 9-14 can choose a 2-dose or 3-dose immunization schedule.
Research data shows that the 2-dose vaccination schedule is effective and safe. As of January 2024, the 9-valent HPV vaccine 2-dose vaccination schedule has 8 years of application experience around the world and has been approved in 88 countries and regions around the world; The World Health Organization's position paper on the HPV vaccine also points out that the primary target group for the HPV vaccine is teenage girls aged 9-14 who have not had sexual intercourse. Vaccination with this group can stimulate a better immune response.
Question 4: Is there any difference between the 2-dose immunization schedule and the 3-dose immunization schedule?
There is no difference between the 2-dose immunization schedule and the 3-dose immunization schedule. The instructions attached to the 9-valent HPV vaccine currently provided by the vaccination clinic are still old versions and can be used for the 2-dose immunization schedule.
At present, in addition to the imported 9-valent HPV vaccine, the domestically produced and imported 2-valent HPV vaccine is targeted at adolescent girls aged 9-14 years old. A 2-dose immunization program is also available. You can choose according to your own situation.
Currently, there are many types of HPV vaccines that have been approved for marketing in my country. Their applicable groups, coverage types, and vaccination procedures are different. You can choose to make an appointment for vaccination according to your own situation. For details, you can consult the community health service center where you live. .
Yangzi Evening News/Ziniu News reporter Yu Dandan