How to achieve clinical cure of hepatitis B? Read the article Protecting Liver Health →
The National Health Commission’s Hospital Management Research Institute and other units have recently launched the “Hepatitis B Clinical Cure Clinic Standardization Construction and Capacity Improvement Project” across the country.
It is planned to build more than 100 hepatitis B clinical cure clinics across the country by 2025 to achieve wide coverage of hepatitis B diagnosis, treatment and clinical cure network.
At present, hospitals in Beijing, Guangzhou and other places have successively opened hepatitis B clinical cure clinics.
Open more than 100 hepatitis B clinical cure clinics by 2025
In the past, hepatitis B was generally considered to be incurable and the virus would be carried for life. Antiviral treatment for hepatitis B can effectively suppress the virus, but it is difficult to eliminate the virus.
With the deepening of research, the concept of "clinical cure" marked by hepatitis B surface antigen negative conversion has been proposed and recognized by liver disease experts at home and abroad. Once clinical cure is achieved, the risk of liver cancer is equivalent to that of healthy people, and antiviral drugs are expected to be discontinued. , patients can achieve the same healthy life as normal people.
The Hepatitis B Clinical Cure Clinic will develop individualized diagnosis and treatment plans for hepatitis B patients and provide one-stop services. The project will also build a national-level disease-specific database.
Wang Guiqiang, director of the Department of Infectious Diseases at Peking University First Hospital: All patients with chronic hepatitis B, that is, those infected with hepatitis B virus, should be included in the management of chronic diseases and should be monitored and followed up regularly.
If he needs treatment, we give him systemic antiviral treatment.
On the basis of antiviral treatment, some suitable groups of people can combine immunomodulators such as interferon to pursue clinical cure and achieve better curative effects.
Therefore, the goal of the Hepatitis B Cure Clinic is not only cure, but actually a concept of whole-process management.
Expand the standards and scope of hepatitis B antiviral treatment
The World Health Organization has proposed the goal of "eliminating viral hepatitis as a public health hazard by 2030". By then, the hepatitis B diagnosis rate will reach 90% and the treatment rate will reach 80%. However, in my country, the current rates are only 22% and 15% respectively.
The new version of chronic hepatitis B prevention and treatment guidelines released by my country proposes a more active prevention and treatment strategy, expands the standards and scope of hepatitis B antiviral treatment, and emphasizes that antiviral treatment is recommended for patients over 30 years old or with a family history of liver cancer as long as they are hepatitis B virus positive. Promote research projects such as antiviral combined with interferon therapy, and continuously optimize hepatitis B treatment plans.
Liver cancer has familial aggregation and early treatment of hepatitis B should be emphasized
Shanghai patient Xiao Wu's father was diagnosed with early-stage liver cancer two years ago, and his mother is a hepatitis B virus carrier. When he was 20 years old, his transaminase index suddenly became abnormal, and he quickly found his father's attending doctor to start treatment.
According to experts, liver cancer has a clear hereditary tendency, and multiple genes may be related to the occurrence of liver cancer. If a direct relative already has liver cancer, the risk of the disease will increase accordingly.
In addition, the familial aggregation of liver cancer is related to the transmission of hepatitis B virus. Vertical transmission of hepatitis B virus in families may lead to the aggregation of liver cancer. If parents are diagnosed with liver cancer, their children will become primary prevention targets. Pay special attention to and early liver cancer screening.
Xie Qing, Director of the Department of Infectious Diseases, Ruijin Hospital Affiliated to Shanghai Jiao Tong University: After hepatitis B virus infection, it can be integrated into liver cells, and then it will cause gene mutations in liver cells, and eventually integrate into the genome, leading to canceration of liver cells. , forming liver cancer.
Therefore, hepatitis B is the most important cause of liver cancer. Treatment of the cause can reduce the risk of liver cancer.
(CCTV News Client)