China News Service, Shanghai, January 31 (Chen Jing and Wang Genhua) Prostate cancer is one of the common malignant tumors in elderly men. With the development of medical technology, although the current mainstream radical surgery for prostate cancer has gradually reduced trauma and accelerated postoperative recovery, a considerable number of patients are still troubled by postoperative complications such as urinary incontinence and sexual dysfunction.

  The reporter visited the Second Affiliated Hospital of the Naval Medical University (Shanghai Changzheng Hospital) on the 31st and learned that the team of Professor Ren Shancheng and Associate Professor Yin Lei from the Department of Urology of the hospital innovatively used "magnetic resonance ultrasound fusion targeted biopsy" plus "high-frequency irreversible electroporation". "Focus Therapy" technology is used to diagnose and treat patients with early-stage, low-risk prostate cancer, achieving both tumor control and functional protection. This precise "millimeter-level navigation" surgery provides new treatment options for many prostate cancer patients.

  Professor Ren Shancheng introduced that prostate cancer is considered a relatively "indolent" malignant tumor. For specific "early-stage, low-risk" patients, "watchful waiting", "radiotherapy" or "radical surgery" can be clinically selected, but these Conventional treatment methods cannot take into account tumor control and functional protection, leaving patients often in a dilemma when choosing. For a long time, doctors and patients have been looking forward to new treatment methods for "early-stage, low-risk, limited" prostate cancer: "more minimally invasive" and "exceptionally precise", which can not only eliminate tumor lesions that have not yet formed, but also treat patients. Get rid of the worry of surgical "cannon-killing mosquitoes".

Professor Ren Shancheng's team carried out precise "millimeter-level navigation" surgery, providing new treatment options for many prostate cancer patients. (Photo courtesy of Shanghai Changzheng Hospital)

  Associate Professor Yin Lei introduced that high-frequency irreversible electroporation is currently considered a promising new technology. This technology uses thin electrode needles inserted into the prostate gland to accurately surround the tumor lesion, and then stimulates a micro-high voltage electric field between adjacent electrode needles to break the outer wall of the tumor cells, causing the death of the tumor cells. At the same time, the normal tissue functions around the lesion can be restored. be effectively protected.

  Mr. Liu (pseudonym), 68, is one of the beneficiaries of this innovative technology. In October last year, he found elevated prostate tumor indicators during a physical examination, and an MRI found: prostatic hyperplasia and local suspicious tumors. Professor Ren Shancheng said: "For the diagnosis of suspected prostate cancer cases, we use the 'magnetic resonance ultrasound fusion, targeted plus template' painless puncture biopsy technology, which can not only effectively determine whether there is a tumor in the patient's prostate, but also understand the location of the tumor lesions. The accurate location and range lay the foundation for subsequent precise treatment." Professor Ren Shancheng's team used this targeted biopsy method to confirm the nature and extent of prostate cancer lesions for Mr. Liu.

  Professor Ren Shancheng and Associate Professor Yin Lei formulated a surgical plan for him using high-frequency irreversible electroporation technology for minimally invasive local precision treatment. During the operation, according to the distribution characteristics of the patient's lesions, Associate Professor Yin Lei inserted five ablation electrode needles in sequence to accurately surround the lesions, and then set the ablation parameters to perform ablation in sequence. The operation was successfully completed in only half an hour. The next day, Mr. Liu resumed eating, got out of bed and moved around, and was successfully discharged from the hospital on the same day.

  It is reported that the postoperative review showed that the ablation effect of Mr. Liu's lesions was satisfactory and the tumor indicators were effectively controlled. At the same time, Mr. Liu's sexual function and urinary control ability were preserved to the greatest extent.

  The Department of Urology of Changzheng Hospital is one of the earliest centers in China that began to explore local treatment technology for prostate cancer. So far, more than 40 clinical cases have been completed using high-frequency irreversible electroporation technology to treat early-stage, low-risk prostate cancer. It is reported that the longest follow-up case is more than 4 years, and the patient's tumor control, urinary control function, and sexual function protection results are all satisfactory. (over)