Zhongxin Wanghai, April 4 (Reporter Chen Jing) Recently, a reporter learned that a "HPV vaccine consumption behavior survey" (hereinafter referred to as the "survey") shows that in China, the awareness rate of HPV vaccine continues to rise, and women of appropriate age have a high willingness to vaccinate HPV vaccine; However, due to the cognitive bias of vaccine application value, and some women of appropriate age will adhere to the "price" to form "vaccine hesitation" and waiting when choosing vaccines, the actual vaccination rate is affected.

In this regard, Professor Zhao Fanghui of the National Cancer Center bluntly said in an interview on the same day that for the prevention of cervical cancer, the bivalent HPV vaccine contains two very important high-risk types: one is HPV16 type and the other is HPV18 type; In China, 84.5% of cervical squamous cell carcinomas are caused by these two high-risk types of infection, and bivalent HPV vaccine has been able to prevent most cervical cancers and precancerous lesions.

This health field survey shows that it is very important to help women of appropriate age correctly understand the value of HPV vaccine, which not only includes the value of life, but also the economic value of individuals, families and even society. It is reported that cervical cancer is a cancer with clear etiology, prevention and control, and the World Health Organization has issued the Global Strategy for Accelerating the Elimination of Cervical Cancer.

Professor Zhao Fanghui said in an interview with reporters that the key to eliminating cervical cancer is to promote the prevention threshold forward and increase the initial investment, and "HPV vaccine + cervical cancer screening" is the key in the key. However, at present, in China, both cervical cancer screening and vaccination coverage still need to be expanded.

In the interview, the reporter learned that it is particularly important to help women of appropriate age correctly understand the value of HPV vaccine, which not only includes the value of life, but also the economic value generated by individuals, families and even society.

At the beginning of this year, the National Health Commission, the Ministry of Education, the Ministry of Civil Affairs, the Ministry of Finance and other ten departments jointly formulated and issued the Action Plan for Accelerating the Elimination of Cervical Cancer (2023-2030), which clearly states that the effective prevention and control and eventual elimination of cervical cancer are achieved through three-level preventive measures such as HPV vaccination, screening, and treatment. In addition to actively strengthening the scientific publicity of HPV vaccination and promoting the pilot work of HPV vaccination, relevant departments have successively launched or announced that they will carry out a region-wide HPV vaccination plan in many provinces and cities to increase the HPV vaccination rate of girls of appropriate age.

Professor Fang Ya, an expert in the field of public health, told reporters that some studies have shown through the construction of mathematical models that if we increase investment in prevention and control, optimize prevention and control strategies, and increase HPV vaccine coverage and cervical cancer screening rate as much as possible, it is expected that by 2047 at the earliest, the incidence of age-standardized cervical cancer in China will be reduced to 4/10,80, that is, to achieve the WHO strategic goal of eliminating cervical cancer, and reduce China's health expenditure by more than 1000 billion US dollars in the next 750 years. 250.<> million cases of cervical cancer and <>.<> million deaths of cervical cancer patients were averted.

Professor Zhao Fanghui told reporters that the HPV vaccine is a preventive vaccine, and the best effect is given before the virus infection occurs. In particular, the immune response is better in adolescent girls aged 9-14 years, and the cost-effectiveness after vaccination is better. Relevant data also show that HPV vaccine in young women has better protective efficacy.

However, the survey shows that not the majority of people recognize the value impact of the HPV vaccine on families. Professor Fang Ya said: "On the one hand, the employment rate of Chinese women is increasing, and their contribution to the family economy is gradually increasing, on the other hand, women still bear the main responsibility of family care in the family. Therefore, reducing the incidence of diseases such as cervical cancer through vaccination as early as possible can not only reduce medical costs, but also reduce the financial burden of patients' families. ”

Professor Fang Ya added that according to cervical cancer epidemiological research, there are two peak periods of high-risk HPV infection in Chinese women, the first peak period is 15~24 years old, and the second peak period is over 40 years old. Therefore, advocating that eligible mothers and daughters be vaccinated together can build a protective barrier for family health.

At present, Chinese women of school-age have more choices, with 5 HPV vaccines to choose from, including: imported two-valent, four-valent, nine-valent, and 2 domestic bivalent vaccines. Compared with high-priced vaccines, bivalent HPV vaccines only cost less than half the cost of vaccination, but protect most cervical cancers, which is a very cost-effective investment. At present, the domestic approved bivalent HPV vaccine (including imported and domestic) only needs to be vaccinated with two doses for women aged 9-14, simplifying the vaccination procedure and reducing the cost of vaccination under the premise of effective prevention of the disease. For families of young age vaccinated, it can also reduce the human, material and financial costs brought by a vaccination.

In addition, Professor Zhao Fanghui said: "In terms of vaccine selection, the most critical issue is vaccine access. If you choose to have an adequate supply of bivalent HPV vaccines, you can immediately achieve protection against 70%-80% of cervical cancer. Therefore, we recommend that you hit whatever seedlings you have, and avoid waiting for a long time. (End)