Chinanews.com, Baoting, Hainan, February 8th (Reporter Wang Xiaobin) "For a period of time, the main bottleneck in the diagnosis and treatment of malignant tumors, in layman's terms, is late discovery, difficult typing, and poor curative effect." At the first Baoting Health Summit Forum and Academician Lecture held in the autonomous county, Wang Hongyang, academician of the Chinese Academy of Engineering and director of the National Liver Cancer Science Center, said in an academic speech that "early diagnosis and early treatment" should be the idea to deal with the challenges of tumor diagnosis and treatment.
Malignant tumors seriously endanger national health.
Citing data from the International Agency for Research on Cancer of the World Health Organization, Wang Hongyang said that in 2020, there will be 4.57 million new cancer cases in China, accounting for 23.7% of the world. In the same year, the number of cancer deaths in China will be 3 million, accounting for 30% of the world.
Malignant tumors with a high mortality rate are mainly concentrated in the digestive system, including liver cancer, esophageal cancer, gastric cancer, and colorectal cancer.
Why are the relative numbers of new cancers and deaths in China so high?
Wang Hongyang believes that early prevention and treatment of tumors has not been realized mainly, and the response rate of patients with late detection is very low in treatment.
Generally speaking, the diagnosis and treatment of malignant tumors in China are currently facing three challenges. The first is late detection, the second is difficult typing, and the third is poor curative effect. , because it cannot be accurately classified, it is impossible to implement accurate personalized diagnosis and treatment for each individual."
"Early diagnosis and early treatment" is the path to break through the bottleneck of malignant tumor diagnosis and treatment.
However, malignant tumors are highly heterogeneous, that is, people have different innate genetic genes and different acquired living environments, so the tumors of different people are also different; in addition, each tumor is in a dynamic evolution process, so early diagnosis requires the development of new diagnosis and treatment Strategy.
Liver cancer is the most heterogeneous malignant tumor known so far. Wang Hongyang took liver cancer as an example to share the practice of improving the early diagnosis rate of liver cancer.
"Liver cancer has a transformation process from inflammation to cancer. This process of inflammation and cancer transformation has caused many patients to be unable to be diagnosed early. How to solve it? It is to change the prevention and control and diagnosis strategies, and diagnose and block before the critical period of inflammation to cancer. to stop and control it," Wang Hongyang said.
Wang Hongyang led the development of "National Multi-center Prospective Liver Cancer Early Warning Screening", and established an early screening program for high-risk groups of liver cancer with my country's independent intellectual property rights.
She also led the team to develop diagnostic reagents with completely independent intellectual property rights, which have been applied in the diagnosis of liver cancer and companion diagnosis of precision immunotherapy.
In addition, substantial progress has been made in technical R&D work such as liquid biopsy screening based on multi-omics molecular markers and visual monitoring of molecular imaging.
Wang Hongyang emphasized that malignant tumors are not only related to individual genes, but also related to environment, ecology, lifestyle, diet structure, psychological emotions and many other aspects, so the individual is the first person responsible for tumor prevention.
For the medical community, the prevention and control of tumors requires interdisciplinary, multi-target, multi-model, multi-modal, and visualized monitoring.
Complex chronic diseases, including tumors, represent one of the greatest challenges of biology in the 21st century.
Wang Hongyang believes that the unique climate advantages and environmental resources of Hainan Baoting and other places are of great significance to the prevention and control of complex chronic diseases.
Under the vigorous promotion of academicians and experts such as Gu Ying and Wang Hongyang, the "Hainan Free Trade Port Health Medical Research Institute" was established and settled in Baoting.
Wang Hongyang revealed that some technologies, including the early screening technology for liver cancer, will be first promoted and applied in Baoting on the platform of "Hainan Free Trade Port Health and Medical Research Institute".
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