China News Service, Beijing, February 4th (Wei Xianghui) A few days ago, Wang Quanyi, deputy director of the Beijing Municipal Center for Disease Control and Prevention, said in an interview with the media that Beijing has established temporary population immunity, and the risk of the recent outbreak of new coronavirus infection is relatively small.

In order to comprehensively assess the infection situation of the new coronavirus and understand the serum antibody level of the community population, Beijing will soon conduct a population serum antibody survey.

What is serum antibody survey?

  According to Wang Quanyi, the survey on the serum antibody level of the Beijing population is planned to be completed from February to March this year.

The survey adopted a multi-stage stratified random sampling survey method, and selected about 5,000 community people from 16 jurisdictions and economic development zones to conduct questionnaire surveys and collect serological specimens.

He said that the study will provide a reference for optimizing resource allocation and preventing and controlling the new crown in the future.

  As early as 2020, the Chinese Center for Disease Control and Prevention has organized and completed the national seroepidemiological survey and analysis of new coronary pneumonia.

The survey covers three types of areas, including Wuhan City, cities and prefectures outside Wuhan in Hubei, and six provinces outside Hubei (Beijing, Liaoning, Shanghai, Jiangsu, Guangdong, and Sichuan). More than 34,000 people in the community were selected by sampling survey design To estimate the infection level of the new coronavirus in the population by detecting the serum new coronavirus antibody of the survey subjects.

Data map.

Photo by Yuan Sui

  The Chinese Center for Disease Control and Prevention explained in the "Scientific Understanding of the Prevalence of New Coronavirus Antibodies in the Population--Questions and Answers on the Results of the National New Coronary Pneumonia Serological Survey" released in 2020 that the serological survey is an epidemic conducted using serological methods and technologies Scientific investigation, through the analysis and research of the distribution of specific antigens or antibodies in the serum of the population and their influencing factors, to clarify the occurrence and prevalence of infectious diseases, and to evaluate the effect of vaccination, etc. 

  Regarding the serum antibody survey conducted in Beijing this time, Wang Quanyi also said that considering that the antibody level will naturally decline over time, dynamic assessment may be carried out in the future as needed.

Why conduct a serum antibody survey?

  Wang Yimin, a physician in respiratory and critical care medicine at the China-Japan Friendship Hospital, introduced to Chinanews.com that the serum antibody detection of the new crown includes specific IgM antibodies and IgG antibodies. More than 4 times higher can be used as the basis for retrospective diagnosis of new coronavirus infection.

  Wang Yimin also said that there may be false positives in antibody testing, such as vaccine recipients, patients with previous immune diseases such as rheumatoid arthritis, etc. Comprehensive judgment of history and antigen or nucleic acid detection.

  Wang Yimin pointed out that the serum IgG and IgM antibodies currently monitored are not completely equivalent to the protective neutralizing antibodies after infection with the new coronavirus, so it cannot be considered that the high antibody titer is related to the "protective power". Antibody detection, the level of this indicator has a certain effect on guiding vaccination, judging the level of overall immune protection and the risk of repeated infection.

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