(Fighting against New Coronary Pneumonia) How to take medicines correctly after pregnant women are infected with New Coronary Virus?

Hear what the experts advise

  China News Service, Chongqing, December 23 (Li Chunmei, Liu Xianglin, Jia Nan) There is no acetaminophen, what medicine can pregnant women take?

What drugs can pregnant women choose to relieve cough?

Can pregnant women take the new crown oral drug Paxlovid?

On the 23rd, the reporter interviewed Quan Shuyan, a clinical pharmacist specializing in obstetrics and gynecology at the Department of Pharmacy, Xinqiao Hospital, Army Medical University, to answer questions about how to take the medicine correctly after a pregnant woman is infected with the new crown.

  Quan Shuyan said that after being infected with the new coronavirus, the main clinical manifestations are fever, headache, sore throat, muscle aches all over the body, nasal congestion, cough and expectoration, etc.

The choice of medication for pregnant women is different from that of ordinary adults. It should not only relieve symptoms, but also not affect the fetus in the abdomen.

  So what should a pregnant woman do if she has a fever?

Quan Shuyan replied that non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in clinical practice to reduce fever.

It can relieve headache, sore throat, muscle aches and other discomforts while reducing fever. Pregnant women are recommended to use unilateral acetaminophen, with a daily dose of no more than 2g (excessive doses may cause serious liver damage), and some Chinese patent medicines also Contains acetaminophen, such as 999 Ganmaoling, VC Yinqiao tablets, etc.

If there is no acetaminophen, you can use ibuprofen or diclofenac sodium before the 28th week of pregnancy. These two drugs also have the effect of reducing fever and relieving headaches, sore throat, and muscle aches all over the body.

  Quan Shuyan said that when a pregnant woman has a stuffy nose and a runny nose, it is recommended to use normal saline to rinse the nasal cavity first. If it cannot be relieved, local use of ephedrine-containing nasal drops (compound nitrofurazone nasal drops for children, a self-made preparation by Chongqing Xinqiao Hospital) or Xyllozoline can be used locally. nose drops.

Ephedrine is the most commonly used nasal decongestant, and the FDA (Food and Drug Administration of the United States) pregnancy classification of oral systemic medication is C grade, and the topical use of a small amount of nasal drops will not cause adverse effects on the fetus.

  What kind of medicine should pregnant women choose for dry cough?

Quan Shuyan said that if the cough affects night rest or normal life, dextromethorphan can be used, and if the curative effect of dextromethorphan is not good, codeine can be used, but it should be noted that it should be avoided in the first trimester, and avoid prolonged, high Dosage, use near delivery, because it may cause respiratory depression and withdrawal symptoms in newborns.

  In terms of expectoration, Quan Shuyan suggested that the mucolytic agent acetylcysteine ​​atomized inhalation is preferred for expectoration during pregnancy. If the drug is not available, ambroxol and bromhexine can also be used. Avoid using it. If you need to relieve cough and reduce phlegm at the same time, you can use Yumei Tablets (compound preparation of guaifenesin and dextromethorphan).

  The new crown oral drug Paxlovid (Nimatevir Tablets/Ritonavir Tablet Combination) has recently been sold in China, can pregnant women take it?

Quan Shuyan said that pregnant women with new crowns who are at risk of severe illness can take Paxlovid tablets.

She said that on November 29 this year, the "Journal of the American Medical Association" published the largest clinical study on the safety and effectiveness of Paxlovid in the treatment of pregnant women with new crowns (45 people completed the study). The study showed that pregnant women infected with the new crown virus can take it safely. Paxlovid reduces the likelihood of severe disease development and does not cause serious side effects in pregnant women and fetuses.

"Expert Advice on Novel Coronavirus Infection During Pregnancy and Puerperium" recommends Paxlovid for severe pregnancy complicated with new coronary pneumonia.

(use up)