Author: Qian Tongxin

  Since December, Hangzhou, Ningbo and other places in Zhejiang Province have started the age-extended vaccination of the nine-valent HPV vaccine.

The first financial reporter noticed that the Zhejiang nine-price HPV vaccine adopts the method of "drawing lots" after registration and appointment, and only those who win the lottery can be vaccinated.

Taking Hangzhou as an example, Hangzhou conducts lottery twice every month on the 8th and 23rd, targeting women aged 9-45 who live, work and study in Hangzhou for a long time.

  It is reported that 600 nine-valent HPV vaccines in the outpatient clinic of Xiangfu Center in Gongshu District, Hangzhou have started lottery appointments. The first appointment is not limited to household registration. The first lottery time is December 8.

The number lottery is carried out through the "Zheliban" App, and the specific process is: user application → organization number lottery → the winning user makes an appointment for vaccination → on-time vaccination.

An ID card can only be booked successfully once, only for the person’s real-name account, and cannot be booked on behalf of others, and cannot be transferred after a successful booking.

  Prior to this, Ningbo had already given birth to the first batch of 60 women who were vaccinated with the nine-valent HPV vaccine "age-extended" through the "number shaking" method.

On the afternoon of December 2, the first vaccination has started.

  In 2014, the nine-valent HPV vaccine was approved for marketing by the FDA for the first time, and it was approved for marketing in China in 2018, suitable for women aged 16 to 26.

The launch of the age-expansion vaccination work means that women aged 9 to 15 and 27 to 45 can also choose the nine-valent HPV vaccine.

  Studies have shown that the top three most common types of HPV infection among Chinese women are HPV16, 52, and 58.

According to the population data in my country, the proportion of HPV types 52 and 58 causing cervical cancer and cervical lesions is higher than the global level.

The nine-valent HPV vaccine covers nine HPV types, including seven high-risk HPV types 16, 18, 52, 58, 31, 33, and 45, and two low-risk HPV types , Type 11.

In other words, the nine-valent HPV vaccine can prevent about 92% of cervical cancer.

  According to experts, the HPV vaccine is best to be vaccinated before the first sexual life, because sexual life will increase the risk of HPV infection, but HPV vaccination beyond the recommended age group will also have a certain effect, and it can also prevent related diseases caused by HPV. Although the effect may not be as good as early vaccination.

  As for the people who have been vaccinated with the bivalent or quadrivalent HPV vaccine, can they be vaccinated with the 9-valent vaccine?

According to the Hangzhou Municipal Health and Health Commission, according to the instructions of the nine-valent HPV vaccine, if you have completed three doses of the four-valent HPV vaccine, you can receive the nine-valent HPV vaccine after an interval of 12 months.

At present, there is no clinical data to support the use of nine-valent HPV vaccine after full immunization with bivalent HPV vaccine.

  In addition, if you are receiving bivalent or quadrivalent HPV vaccine, can you switch to 9-valent HPV vaccine?

The Hangzhou Municipal Health and Medical Commission stated that according to the recommendations of the World Health Organization, there are currently limited clinical studies on the sequential vaccination of bivalent, quadrivalent and nine-valent HPV vaccines, so the safety and effectiveness of such vaccinations are unknown.

Therefore, it is not recommended to exchange HPV vaccines of different valence types.