Parkinson's disease, an intractable disease that causes the body to become immobile, is said to be caused by the accumulation of abnormal proteins in the brain, but groups such as Osaka University have found a new type of Parkinson's disease that seems to be caused by another substance. I announced that.

This research was conducted by a group such as Goichi Betsumiya, a specially appointed lecturer at the Graduate School of Medicine, Osaka University.



Parkinson's disease is an intractable disease that causes tremors in the limbs and immobility, and is caused by the accumulation of an abnormal protein called "α-synuclein" in a part of the brain.



The group received a postmortem brain donation from a patient diagnosed with Parkinson's disease and, upon closer examination, found that another protein called "TDP-43" was accumulated instead of "α-synuclein." I understand.



Although it has been pointed out that "TDP-43" is associated with other intractable neurological diseases, it is not known to cause Parkinson's disease, and the group considers it to be a new type of Parkinson's disease.

"Although it is an analysis of one case, I think it was a discovery that puts a stone in the research to elucidate the cause of Parkinson's disease," said Betsumiya.