(Shanghai War Epidemic Record) The number of positive infections in Shanghai is still at a high level. Repeated nucleic acid testing is very necessary

  China News Service, Shanghai, April 17 (Reporter Chen Jing) At the press conference on the prevention and control of the new crown pneumonia epidemic in Shanghai held on the 17th, Wu Jinglei, director of the Shanghai Municipal Health Commission, said that positive infections found in risk groups The proportion is declining.

The number of positive infections found in the past two days is still high, but relatively stable.

  On the 16th, Shanghai added 3,238 local confirmed cases of new coronary pneumonia and 21,582 local asymptomatic infections.

307 confirmed cases and 415 local asymptomatic infections were found in nucleic acid screening of relevant risk groups.

Wu Jinglei explained that among the 3,238 local confirmed cases, 1,754 were found in closed-loop isolation and control, 307 were found in nucleic acid screening of relevant risk groups, and 1,177 were asymptomatic infected persons who were transferred to confirmed cases, and the actual new confirmed cases were 2061 cases.

  He said that Shanghai will focus on key points, zoning and grading, and implement nucleic acid screening as the main method, supplemented by antigen screening, and implement full-staff testing and screening for personnel in the closed control area, control area, and prevention area, and will be based on staged screening. According to the results of the investigation, we will dynamically adjust the delineation of the "three districts", and strive to achieve the goal of social clearance in the shortest possible time.

  Currently, 16 severe cases are being treated in hospital.

Wu Jinglei said that among the 16 severe cases, the youngest was 33 years old, and the others were elderly people over 70 years old.

Of the 16 people, only one was vaccinated throughout the course, and none of the others had been vaccinated against the new coronavirus.

Wu Jinglei said that the 33-year-old patient suffered from a severe autoimmune disease, and his immune function declined significantly; at the same time, he had poor kidney function and required hemodialysis maintenance.

At present, after active antiviral symptomatic treatment, combined with traditional Chinese medicine treatment, the patient's lung imaging has improved, and related underlying diseases are still being actively treated.

Other elderly critically ill patients have serious underlying diseases.

  He said that in accordance with the principle of "one person, one plan", the designated hospitals will increase the treatment force and carry out multidisciplinary expert consultations. According to the characteristics of severe patients with serious underlying diseases, while actively treating new coronary pneumonia, they will provide ventilator-assisted ventilation, extracorporeal Model lung (ECMO), antiviral, anti-infective, symptomatic nutritional support and other treatments.

Wu Jinglei said that the designated hospitals pay special attention to the treatment of these critically ill patients with traditional Chinese medicine, which complements the advantages of modern medicine and western medicine.

The medical staff also paid special attention to observe the changes in the condition of critically ill patients and made every effort to treat them.

  Nucleic acid detection is an important means of prevention and control of new coronavirus infection.

At present, Shanghai is still carrying out high-frequency repeated nucleic acid testing?

Gao Chunfang, director of the Testing and Experiment Center of Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, said that repeated testing is necessary to detect positive infections.

Through population nucleic acid testing, cases, especially asymptomatic infections, can be detected as soon as possible, risk areas and key groups can be identified and locked, and targeted control measures can be taken in a timely manner to stop the spread of the epidemic.

  Gao Chunfang said that in terms of the occurrence and development of clinical diseases, any pathogen infection has a certain incubation period, and the new crown is no exception, and there are certain individual differences in the length of the incubation period.

From the perspective of detection technology, there is the concept of detection window period.

After virus infection, there is a growth and replication process in the body. In the early stage of infection, the viral load is too low, below the lower limit of detection, and positive can not be found. This time period is the detection window period.

The expert said that the incubation period of infection + the detection window period makes it impossible to detect positive results in the early stage of infection. Repeated testing can increase the probability of positive detection and timely detection of positive results.

  It is reported that since the sampling of respiratory pathogens mainly adopts several forms of throat swabs, nasal swabs, and nasal + throat swabs, there are inevitably certain sampling differences in the sampling process.

This difference includes the sampling site, depth, and the amount of secretions collected.

Therefore, repeated sampling and testing can make up for the possible false negative effects caused by sampling errors.

  Gao Chunfang said, in addition, for those who have been infected, during the development of the disease, repeated detection and monitoring of load changes provide a good indicator for predicting the treatment effect and recovery status of infected patients.

Repeated testing is a routine practice for clinical pathogen confirmation. For example, for other infectious diseases such as urinary tract infection and blood tract infection, multiple culture (more than three times) monitoring is usually required to confirm positive pathogens and achieve precise treatment.

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