• Gynecology Two studies affirm that anti-Covid vaccines affect menstruation

  • Health These are the changes in the breast and in menstruation suffered by women recently vaccinated against Covid-19

Many people who do not usually menstruate reported

experiencing intermittent bleeding or other symptoms of menstruation after receiving the Covid vaccine,

according to the results of an

online

survey conducted by researchers at Washington University in St. Louis.

This research is the first to examine vaccine-associated breakthrough bleeding in people taking testosterone or other hormones that suppress menstruation.

The research focuses on

people with different gender identities

such as transgender, non-binary or gender fluid.

Previous studies of vaccine-related menstrual symptoms have focused primarily on cisgender (cis) women, that is, those whose identity matches the female gender from birth.

"It is important to examine the impact of the Covid-19 vaccine on menstruation and breakthrough bleeding in people who are not cis women, as they are too often left out of the discussion," said Katharine Lee. , Ph.D., postdoctoral research fellow in the Division of Public Health Sciences at Washington University in St. Louis, and first author of the study.

"I hope

this study adds to the growing evidence that perhaps we should include periods as part of vaccine research more broadly.

.

Our findings also underscore the importance of including gender-diverse people when studying parts of biology that are closely tied to sex-based reproductive physiology, such as periods."

Lee will present the results of the study at the annual meeting of the American Anatomy Association during the Experimental Biology 2022 meeting, which takes place in Philadelphia from tomorrow, April 2, until next Tuesday.

Calendar and symptoms

Researchers have previously reported that some people with regular or predictable menstrual cycles experience changes in the timing or symptoms of their periods after receiving the Covid vaccine, although these changes are usually temporary and there is no evidence that fertility is affected. be affected.

For the new study, Lee and her colleagues analyzed a subset of responses to an online survey about menstrual experiences after vaccination to get specific information about people who don't usually menstruate.

Of the more than

160,000 people who responded to the survey, the researchers identified 552 people who said they used testosterone or other gender-affirming hormones and did not usually menstruate.

The majority of these respondents (84%) selected more than one gender category, with 460 identifying as transgender, 373 identifying as male or male, 241 identifying as non-binary, and 124 indicating non-conforming. gender

(genderqueer)

.

A third of those surveyed said they had intermenstrual bleeding after receiving the Covid vaccine, 9% said they had chest or breast pain, and 46% said they had other symptoms that they would normally associate with menstruation, such as cramps and bloating. .

Some respondents used the open-ended text boxes in the survey to report

significant negative mental health effects in response to period symptoms, such as anxiety, depression, gender dysphoria, panic attacks, and suicidal ideation.

Clinical trials of Covid vaccines have not generally examined impacts on menstrual experiences.

Consequently, these potential effects are not mentioned in the safety information provided to vaccine recipients.

Mental health effects

"I'm hoping that discussing these findings openly will let people know that this could be a side effect so they can prepare appropriately," Lee said.

"This is especially important given the fact that some people described mental health outcomes such as anxiety, depression and suicidal ideation as responses to unexpected bleeding after vaccination."

Lee added that a better understanding of the potential side effects of menstruation

can help address the needs of medically underserved populations, including gender-diverse people

, as well as help reduce vaccine hesitancy.

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