The anti-Covid vaccine is associated with minimal changes in the menstrual cycle

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• Covid-19 This is what changes in the breast and menstruation suffered by women recently vaccinated against Covid-19

Research promoted by the American National Institutes of Health (NIH) concludes that the impact of COVID-19 vaccination on the menstrual cycle is very limited. According to this study, a dose of the covid-19 vaccine can

the menstrual cycle (the time between bleeding) by one day during a single cycle, something that they consider to be within the

. It does not influence the number of days with bleeding. This is how they have seen it when comparing vaccinated women with others who were not, as explained in 'Obstetrics & Gynecology'.

However, the researchers in this work acknowledge that more research will be needed to determine whether the covid vaccine can potentially influence other effects of the cycle, such as

(pain, mood swings, etc.) and

characteristics .

The researchers, led by

, a professor at Oregon Health & Science University in Portland, evaluated 23,754 menstrual cycles of

(of whom 2,403 were vaccinated). Most of the women received the

(Pfizer-BioNTech and Moderna). The change in the cycle that they attribute to the covid vaccination (just one day of variation in the cycle)

highlight.

Among women who received the two doses of the vaccine within the same menstrual cycle (358 vaccinated) there was a greater increase in cycle length of two days on average. About

of these women experienced a change in cycle length of

, although this variation was attenuated in the two menstrual cycles that followed vaccination. The authors point out that the International Federation of Gynecology and Obstetrics classifies a variation in the duration of the cycle as normal if it is less than eight days.

"It 's

that the study found only a small temporary menstrual change in women," says Diana W. Bianchi, director of the National Institute of Child Health and Human Development (NICHD) Eunice Kennedy Shriver at NIH. "These results provide, for the first time, the opportunity to

women on what to expect from vaccination against COVID-19 so that they can plan accordingly."

To carry out this work, the researchers used a

monitoring app , with which users provide data on their temperature and menstrual cycles.

They studied

consecutive to vaccination, including the cycle or cycles in which the doses were administered.

The data were compared with those of six consecutive cycles of unvaccinated people.

"The mRNA vaccines create a strong immune or stress response, which could temporarily affect the

if it becomes synchronized. Our findings in individuals who received two doses in a single cycle support this hypothesis," write these scientists. .

The time of the menstrual cycle is regulated by this axis, which can be affected by exogenous stressors. With the two mRNA vaccines guidelines (21 days for Pfizer and 28 days for Moderna), a person receiving

in a single cycle would have received one at the beginning of the follicular phase. This phase, with the maturation of the follicle, influences the variability of the duration of the cycles, explain the authors, who recall that a severe acute disease such as

for the function of the hypothalamic-pituitary-ovarian axis. sometimes permanently ".

The study did not observe changes in the menstrual cycle of unvaccinated people, so they rule out that their results are explained "by generalized pandemic stress, because our

not see changes in a similar period of time."

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