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Wild deer are also susceptible to SARS-CoV-2 infection.

This is demonstrated by an investigation published this Thursday in

Nature

, which proves the contagion of multiple specimens of white-tailed deer (

Odocoileus virginianus

) in Ohio (USA).

The animals were carriers of viruses from humans and, according to the evidence from the work, it is possible that transmission between them also occurred. The finding shows that deer could be a

reservoir

for the virus and, therefore, a

niche for the development of new variants

.

Deer are not the only animal species in which SARS-CoV-2 infection has been demonstrated. Infections have been identified in domestic animals, such as cats, and also in housed species, such as mink. In fact, at the end of last year Denmark euthanized more than 15 million farmed minks destined for the fur industry after detecting reciprocal infections between mink and humans. Several laboratory studies had also shown the

possible susceptibility of cetaceans, primates or rodents

. However, to date there was not much evidence of the presence of the virus in wild animals, such as deer.

"The potential establishment of a new reservoir of SARS-CoV-2 in white-tailed deer could open new pathways to evolution, transmission to other wild species, and potential leaps of new variants not known to our immune system to humans", The authors of the work, led by researchers from the University of Ohio (USA), point out in the scientific journal, who claim to strengthen epidemiological surveillance in this regard.


Between January and March 2021, these scientists collected nasal samples from 360 deer in nine areas of northeastern Ohio, all relatively close to built-up areas.

After an analysis with RT-PCR, they found that

129 of them, 35.8%, were positive for SARS-CoV-2

.

In four of the locations analyzed, the deer were carriers of

the B.1.2 virus,

precisely the type of coronavirus predominant at that time in the Ohio population.

In the genetic analysis of the samples, infections with lineages

B.1.582

and

B.1.596

were also identified

.

The researchers were able to demonstrate at least six different transmission chains from humans to deer.

But in addition, the research also allowed to uncover the existence in some of the samples of mutations in protein S rare in humans, which, as suggested in the scientific journal, could be indicative of transmission from deer to deer.

It is a hypothesis that should be confirmed, say the researchers.

In their conclusions, the researchers underscore the importance of the finding and the need to "expand the monitoring of SARS-CoV-2 in potential wild hosts in order to document the extent of the problem, understand the ecology of transmission, and analyze the trajectory. evolutionary ", they indicate.

"It is alarming that a third of the animals in the study tested positive on PCR,

suggesting an active or recent infection

," they add.

When living in an environment close to urban areas, deer could have come into direct or indirect contact with sources of contagion (garbage remains, feces, etc.) capable of facilitating the transmission of the virus in susceptible species.

Hops between virus species are of particular concern because they involve significant mutations in the virus. To adapt to a new species, the virus must undergo changes much more profound than those that occur in transmissions within individuals with similar characteristics. And these

evolutionary leaps

open the door to new variants of interest.

"Viruses are constantly evolving. It is difficult to stop them precisely

because of their ability to change and adapt

. For this reason, it is important that studies be carried out in the laboratory, with cells from different species of animals, to know which ones are susceptible to becoming infected [which they open their cells with the protein S key] and in which cases it would be necessary to take special precautionary measures ", explained a few months ago, following the detection of jumps of the virus between mink and humans, Isabel Sola, head of the Laboratory of Coronavirus from the National Center for Biotechnology (CNB-CSIC).

Public Health experts have long recalled that human health is not a watertight compartment, but rather goes hand in hand with animal health and the health of the planet.

Coordinating surveillance and efforts so that these three areas are aligned is one of the pillars to protect against future pandemics.

According to the criteria of The Trust Project

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