[Explanation] Recently, there have been many new cases of Omi Kiron strain infection worldwide.

What are the characteristics of the Omi Keron strain?

How infectious is it?

Will it make existing vaccines useless?

On December 4, when participating in the dialogue with the academicians of the main forum of the Second Greater Bay Area (Shenzhen) Vaccine Summit, Zhong Nanshan, an academician of the Chinese Academy of Engineering, shared the recent research results and experimental data of relevant institutions with the representatives of the experts through a video connection. , And gave his own latest judgment on these issues.

  [Explanation] Zhong Nanshan introduced that according to overseas media reports, compared with the tens of thousands or hundreds of thousands of previously reported cases of the new crown, the current number of reported cases of Omi Keron is not too high. China should still stick to the "dynamics". There is no need to be afraid of the Omi Keron strain of the epidemic prevention measures.

  [Explanation] Regarding the "immune escape" that the Omi Keron mutant may bring, Zhong Nanshan believes that now is not the time to adjust the vaccine urgently.

  [Concurrent] Zhong Nanshan, Academician of Chinese Academy of Engineering

  Our inactivated virus vaccine should say that it covers a wide range of antigens. Although its protection rate is slightly lower, it should be the widest (coverage). I believe it will not be completely ineffective against Omi Keron.

It should not be difficult to change this (vaccine virus strain), but the price is very high if it is changed.

So one is to look at the spread of Ome Keron, and more importantly, it depends on the incidence of Ome Keron.

If its pathogenicity rate is not as terrible as we think, and now according to the relatively one-sided news I know, many doctors in South Africa believe that the disease caused by Omi Keron is relatively mild in general. Under such circumstances, we will gradually treat it like the flu in the future.

So I think this is not a time for urgent adjustments. We need to wait about two or three weeks later to see its development trend. I think it can explain the problem.

  [Explanation] At present, 1.125 billion people in China have completed the entire course of COVID-19 vaccination, accounting for 79.76%.

However, whether it is a whole virus inactivated vaccine or an mRNA vaccine, the humoral immune function has been significantly reduced after half a year of a course of treatment. At present, countries are discussing how to strengthen immunity.

Which strategy is more effective for "enhanced shot" vaccination?

In this regard, Zhong Nanshan shared.

  [Concurrent] Zhong Nanshan, Academician of Chinese Academy of Engineering

  After two doses of inactivated virus vaccines, the third dose of the original vaccine is effective, and this is proven in the real world, and its clinical protection is enhanced.

  Will there be such a situation?

Vaccination of a different type of vaccine may be more effective as a booster, but this thing, I once again emphasize, this result is similar to the real world, is its protection rate the same?

The time is too short to explain the problem.

  [Explanation] Since 2020, the prevalence and death rate of new coronary pneumonia in China have been the lowest in the world. How can normalization be restored?

Zhong Nanshan proposed two premises and three prevention and control measures.

  [Concurrent] Zhong Nanshan, Academician of Chinese Academy of Engineering

  What is the premise of my personal opinion? The (new crown) case fatality rate will decrease.

(New Crown) The fatality rate has dropped to about 0.1%, and it is still a little bit or two in the world. If it is about 0.1%, it will be a bit like the flu. If this is the case, it may coexist.

Then there is the replication index. The spread of the replication index is also reduced. The situation is like the flu. This is the premise.

So how to achieve this premise and what are the measures?

Everyone has made it clear that all people must be vaccinated to establish herd immunity, which is very important; the second is the normalization of community prevention and control; the third is definitely the development of effective drugs and antibodies, and so on.

The problem we need to pay attention to now is to strengthen the vaccination of the elderly, especially those over 70 years old.

  (Reported by He Junjie, Shenzhen, Guangdong)

Editor in charge: [Wu Qingcai]

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