Three women and a premature baby were killed in a fire in the Lower Bavarian district of Dingolfing-Landau.
According to initial findings, another 23 people were injured, said a local police spokesman on Saturday morning.
Three of the injured had to be taken to nearby clinics.
Any help came too late for the 78, 55 and 20 year old women and the baby.
How the fire in the apartment building in the center of Reisbach came about was still completely unclear on Saturday morning.
The fire spread throughout the house during the night.
A large number of fire brigade, rescue workers and the police were on site.
A police helicopter was also used.
The extinguishing work has not yet been completed.
"Bricks are still falling from the roof," said the police spokesman that morning.
The apartment building could therefore not yet be entered.
The Landshut criminal police took over the investigation on site.
According to the officials, 27 residents are registered in the house.