• Livei All the last hour of the coronavirus

  • Covid-19 One of the Spanish vaccines could begin to be tested in humans in spring

The Spanish Agency for Medicines and Health Products (AEMPS) has not given the go-ahead for the MVA-COVID-19 (S) vaccine test, developed by Mariano Esteban's team at the National Center for Biotechnology (CNB-CSIC) together with Biofabri, it will not go to the trial phase with human beings, as confirmed by the Hospital de la Paz in Madrid to EL MUNDO, reports

Marta Belver.

The Spanish vaccine against coronavirus will not go to the human trial phase as it does not receive the approval of the Spanish Agency, as the CSIC and Biofabri have communicated to La Paz, which was working on the selection of volunteers to administer the Spanish serum, as El Español has advanced.

Last January, it was expected that the vaccine of Mariano Esteban and his team, based on an attenuated variant of the smallpox virus (MVA) and that had concluded its tests in animals with outstanding, showing 100% efficacy, would receive in this past spring the approval of the Spanish Agency of Medicines.

"We have to postpone the start of the clinical trial without a scheduled date," the Madrid hospital in La Paz said this Saturday.

The doubts have arisen after the death, due to lung injuries, of one of the macaques that were inoculated with the CSIC serum during the animal tests.

Mariano Esteban and Biofabri's team had been working for months on their 'pretty girl' (MVA-CoV-2-S), capable of expressing the protein (S) of the new coronavirus.

In animal models, it induces neutralizing antibodies and a cellular response of T lymphocytes

, which are the cells in charge of recognizing and destroying the infected cell.

They trusted this prototype because when applied to other emerging viruses such as chikungunya, Ebola or Zika, as the researcher pointed out last August, "it had shown an efficacy in animal models of 80% -100%, that is why we consider it a good candidate".

In this case, the effectiveness reaches 100% when it comes to stimulating the immune defenses against Covid-19, according to a study published in the journal 'Virology'.

According to the criteria of The Trust Project

Know more

  • Coronavirus

  • Vaccines

  • Covid 19

  • Science and Health

Coronavirus How many days does it take to achieve immunity with each vaccine?

Health Why does the Covid vaccine hurt?

VaccinesThe pandemic caused the largest disruption in childhood vaccination in history

See links of interest

  • Last News

  • Work calendar

  • Home THE WORLD TODAY

  • Master Investigation Journalism

  • Novak Djokovic - Pablo Carreño, live

  • Spain - Ivory Coast, live

  • Hungary - Spain, live