A large-scale group such as the University of Tokyo has compiled analytical data such as what genes work and how much in the immune cells of patients in Japan in order to elucidate the mechanism of diseases caused by immune abnormalities such as rheumatoid arthritis. I have created a database.
This is the first time that an Asian person has such a database.
This database was created by a group of the University of Tokyo and RIKEN and published in the international scientific journal "Cell" dated 30th.
The group received blood from 416 people in Japan, including patients, for 10 types of diseases caused by immune disorders such as rheumatoid arthritis, and what genes and how much are expressed in each of the 28 types of immune cells contained therein. Was analyzed in detail and summarized in the database.
Using this database, for example, in the case of systemic lupus erythematosus, which causes inflammation throughout the body, it can be expected to be useful for research, such as immediately finding out that 20 genes have unusual reactions.
Such a database already existed in the United States, but it is the first to target Asians, and the registered data is the largest in the world.
Minehito Ota, a specially appointed assistant professor at the University of Tokyo, said, "If you look at the database, you can see exactly which gene of which immune cell is involved in the disease. I hope it will help you to clarify the mechanism of the disease."