Coronavirus: France authorizes Eli Lilly monoclonal antibody treatment (Illustration) -

Handout / National Institute of Allergy and Infectious Diseases / AFP

France has granted a temporary authorization for use for monoclonal antibody treatment from the American laboratory Eli Lilly for mild to moderate symptomatic forms of Covid-19 in non-hospitalized adults at high risk of severe forms, we learned. this Thursday with the Medicines Agency.

This is the first anti-Covid monoclonal antibody available in France, for its part the Directorate General of Health (DGS) said in a note.

“To ensure maximum effectiveness, this treatment (which uses an antibody called bamlanivimab) should be administered within five days of the onset of symptoms.

The effectiveness of this treatment on the so-called South African and Brazilian variants has not been demonstrated, ”according to this note.

Hospital administration

"It is indicated for the treatment of mild to moderate symptomatic forms of Covid-19 in adults not hospitalized for Covid with a positive virological test for SARS-CoV-2, and at high risk of progressing to a severe form of Covid-19 ”, the same source continues.

As part of this temporary authorization, this treatment can only be prescribed by a hospital doctor and must be administered intravenously in the hospital, it is detailed.

The recommended dose of bamlanivimab is a single 700 mg intravenous infusion given over 60 minutes, the ANSM said.

This treatment targets in particular patients over 80 years old, organ transplant recipients such as kidney transplant recipients, dialysis patients, patients undergoing chemotherapy ... This antibody “works well against the British variant (of Sars-CoV-2), this which is precious, while this variant will become dominant, ”said Brigitte Autran, expert in immunology at Sorbonne University.

The Eli Lilly laboratory produces this treatment in Fegersheim (Bas-Rhin).

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