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At 2.40 p.m. local time (8.40 p.m. CET), contact with the plane was broken, said Adita Irawati, a spokesman for the Indonesian Ministry of Transport.
About 45 minutes after the start, contact was broken.
The normal flight time for this route is approximately 90 minutes.
According to Flightradar24, the machine had previously lost almost 3,000 meters in height within a minute.
According to "Sky News", the Indonesian has started a rescue mission.
According to the airline, there were 56 passengers and six crew members on board.
The industry service "Aviationherald" reports of a kind of dive of the aircraft after the last received, automatically sent data (ADS-B).
The machine then erected a height of around 3.2 kilometers just four minutes after take-off.
Then the Boeing sank within 20 seconds to a height of only 400 meters.
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The aircraft that has disappeared is a 26-year-old Boeing 737-500, i.e. not the unlucky 737Max, which is currently back in service in the USA after a flight ban.