The authorities in Botswana, Africa, are investigating the death of at least 350 villas in a few weeks, and in unclear circumstances.
The cause of death of these animals has not yet been revealed, but the government has ruled out the possibility of animals being poisoned by humans, or being infected with anthrax.
According to the German "Die Welt" website, samples were sent for analysis in South Africa, Zimbabwe and Canada.
According to Neil McCain, director of Wildlife Conservation at the National Salvation Park charity, the situation is "catastrophic", calling for further investigations to find out the causes of elephant mortality.
In an interview with Britain's Sky News, McCain said the death toll is very high, adding: "Botswana is home to a third of the African elephants, and 10 percent of them are in that region, and here the risk lies."
"It is important to know the reason behind the death of so many elephants, the possibility of exposure to a virus is contained. We must discover the secret, the disease that infected animals may be transmissible to humans," McCain added.
For his part, director of "Elephants Without Borders" Michael Kayes revealed that some of the elephants were suffering from severe weakness and lethargy before their death, as some noted that they were limping during movement and were largely confused.
This prompted some scientists to believe that the elephants were infected with a disease attacking their nervous system.
The dead elephants were found lying on her stomach, which indicates a quick and sudden death. Many were also close to natural water sources, according to the German website de Welt.
Scientists rule out water poisoning, otherwise they would have found dead birds also next to elephants. These birds feed on the carcass of other animals.
It is noteworthy that Botswana has about 13,000 elephants, which is equivalent to a third of the elephants on the African continent.