The effect is the vitality of Chinese medicine

Interview with Academician Huang Luqi

Early in the morning on April 8, Huang Luqi, an academician of the Chinese Academy of Engineering, turned on the TV and watched the news covering Wuhan ’s unblocking in real time. "Remembering that when we first arrived on New Year's Day, there was no one car on the road, I really wanted to stay, to stay to witness this moment, witness the unsealing, witness the recovery, and witness the excited mood of Wuhan people. "Said Huang Luqi, who returned to Beijing on the evening of April 7.

Huang Luqi was born in Wuyuan, Jiangxi in 1968. He received a doctorate degree from Peking University Medical Department (formerly Beijing Medical University) at the age of 27. He became a doctoral tutor at the age of 31. He became the chief scientist of the National 973 Program at the age of 38. Dean of the Academy of Sciences, mainly engaged in the research of Chinese medicine resources and molecular pharmacology, and the research on anti-cancer and anti-AIDS in the genus Trichosanthes is ahead of the international level.

"I chose to return to Beijing 4 hours before the unblocking. If a person has done a good job, he should stand back." Huang Luqi said in an interview with our reporter.

As soon as we set foot on the "battlefield", we all became brave and fearless

Q: What was your mood when you rushed to Wuhan?

Huang Luqi: I asked to go to Wuhan on my own initiative. I didn't have time to think about it. Rescuing patients is the responsibility of a medical worker, and it is also the time to test the original mission of our party members. Only on the front line, seeing the true situation of the epidemic in person, and discovering the problems and difficulties encountered on the front line, can traditional Chinese medicine play a better rescue role in the fight against the epidemic. When we come, we can fight side by side with Western medicine and cooperate with Taiwan.

Q: Was the family worried at the time?

Huang Luqi: Worry is for sure. My mother is 84 years old this year and is a local Chinese medicine practitioner in Wuyuan, Jiangxi. When I learned that I was in Wuhan, I was very worried about my health and safety. My sister sent a text message to her mother: "He is your son and the doctor of the people. In this case, his duties must be done. How can he escape? How much do you understand him, the medical staff fighting on the front line They are also the darlings and children of their parents. They are more dangerous and harder. I only hope that everyone will work together to overcome this disease as soon as possible, come back safely, and return peace to the world.

Q: Do you remember what happened when you first arrived in Wuhan?

Huang Luqi: On January 25, the first day of the Chinese New Year, I took the first national TCM medical team composed mainly of clinical staff from Xiyuan Hospital and Guanganmen Hospital of the Chinese Academy of Chinese Medical Sciences from Beijing and rushed to Wuhan by high-speed rail. . On the day of departure, it happened to be the 29th birthday of Chen Yingying, a member of the medical team. Without preparing a gift in advance, everyone gave her a mask on the high-speed rail, wishing her a safe triumph. Before arriving, frankly, the medical team members were still a little worried and scared, but when they arrived in Wuhan, they saw that the streets were empty and there were only ambulances travelling. Then we knew that we had stepped onto the "battlefield" and everyone Have become brave and fearless, and a sense of responsibility and mission emerged spontaneously.

Question: What difficulties and challenges have you encountered since you arrived in Wuhan?

Huang Luqi: After arriving, our first batch of national TCM medical teams took over an independent ward of Jinyintan Hospital, focusing on the treatment of severe and critically ill patients, the pressure is still very great. Jinyintan Hospital is a three-level infectious disease specialist hospital. There are some differences in the working philosophy and procedures of the Western Medicine Hospital from the Chinese Medicine Hospital. In-depth communication is needed on how to integrate Chinese and Western medicine and how Chinese medicine can function. At the same time, Jinyintan Hospital uses less Chinese medicine, lacks Chinese medicine, and does not have a Chinese medicine prescription information system, which has caused difficulties for the deep participation of Chinese medicine. Under the policy guidance of equal emphasis on Chinese and Western medicine and the combination of Chinese and Western medicine, the medical team cooperated with Jinyintan Hospital to add a Chinese medicine prescription information system, increase drug protection, and quickly entered the battle to effectively play the role of Chinese medicine.

Q: What is the main job of the team after returning to Beijing?

Huang Luqi: Under the strong leadership of the Party Central Committee, the epidemic prevention and control has achieved important results in stages. From 0:00 on April 8th, Wuhan lifted the control measures for the separation from Han to Hubei, orderly restored external traffic, and our medical team has all returned to Beijing and is undergoing isolation and recuperation. The work is mainly to summarize the experience of treatment in Wuhan, to prepare for the global epidemic prevention and treatment and "going out" of Chinese medicine, on the other hand is to restore daily work in an orderly manner.

It is the real effort to cure the disease clinically

Q: When you first arrived in Wuhan, did you have confidence in the prevention and treatment of new coronary pneumonia with Chinese medicine?

Huang Luqi: As a Chinese medicine person, we believe in the treasure left by our ancestors. Before leaving, I learned that a patient with new coronary pneumonia who was discharged from hospital was cured by a combination of Chinese and Western medicine. This makes us more convinced that Chinese medicine can play its due role in the prevention and treatment of new coronary pneumonia.

On the way, I kept thinking, as the dean of China Academy of Chinese Medical Sciences, what is my mission to lead the medical team to Wuhan? One is to cure people and save others, and the other is to give play to and prove the advantages and characteristics of Chinese medicine. If a core party can be formed, and the core party will be developed into a new Chinese medicine specializing in the treatment of new coronary pneumonia, this is the blessing of traditional Chinese medicine, the blessing of the country, and the blessing of the people.

After arriving in Wuhan, we will treat, summarize and study. The first batch of 8 patients in the ward that was taken over was discharged from the hospital on February 3, and we have established confidence. On February 19, we were determined to achieve zero deaths in the ward, and finally did it. Our confidence is self-evident.

Q: Did you find this new Chinese medicine?

Huang Luqi: At the press conference held by the State Council not long ago, I mentioned Huashibaidu particles. This is the first new Chinese medicine for the treatment of new coronary pneumonia with complete intellectual property rights in China.

According to the clinical characteristics of the disease, I and academician Zhang Boli, academician Tong Xiaolin and other first-line Wuhan experts, as well as academician Wang Yongyan in Beijing, Chinese medicine master Chao Enxiang, Chinese medicine master Xue Boshou and other remote connections, jointly discussed the national TCM diagnosis and treatment plan, in the national diagnosis and treatment plan On the basis, we have optimized the prescription of Huashi Baidu. After obtaining this prescription, we conducted heavy-duty, light-weight, and ordinary-type clinical efficacy observation and case accumulation in Jinyintan Hospital, Dongxihu Fangcai Hospital, and Jiangjun Street Community Health Center, respectively. At the same time, the Chinese Academy of Chinese Medical Sciences launched an emergency task to complete the hospital preparation. On March 18, Huashibaidu Granules was awarded the first clinical trial approval of a new Chinese medicine for the treatment of new coronary pneumonia.

Q: This time, patients with new coronary pneumonia have a high degree of recognition for Chinese medicine treatment, why?

Huang Luqi: The curative effect is the vitality of Chinese medicine. Clinical treatment can never be falsified. Only clinical treatment can cure diseases. From the clinical effect, the effective performance of Huashi Baidu Granules has been well confirmed.

In response to the outbreak of New Coronary Pneumonia this time, from the prevention and control of close contact with the population to the treatment of light and ordinary patients and heavy and critically ill patients, Chinese medicine has participated and played a role in the whole process. Studies have confirmed that the combination of Chinese and Western medicine can quickly improve the symptoms of fever, cough, and fatigue, shorten the length of hospitalization, increase the negative rate of nucleic acid conversion, effectively reduce the development of light and ordinary types from heavy to heavy, and from severe to critical, improve the cure rate and reduce Mortality rate. Take the ward managed by the National Chinese Medical Team as an example, this ward is mainly for severe patients. As of March 30, the medical team had returned to Beijing. A total of 158 patients were admitted to the ward, including 124 severe cases and 26 critical cases. At present, 140 patients have been discharged and the rate of cured discharge is 88.61%.

Medicine is a human science with temperature and needs "empathy"

Question: In your opinion, what kind of occupation is "healer"?

Huang Luqi: "Sometimes to cure, often to help, always to comfort", the epitaph of American doctor Trudeau said the essence of medicine. Medicine is not a simple science, but a human science with a temperature and a need for "empathy". It needs to pay attention to humanistic care, give patients the necessary respect and understanding, consider themselves to the patients, and warm the patients while also warming the doctors themselves. If you don't see anyone, you must insist that love and technology go hand in hand.

I was deeply touched by the recovery process of a patient. The 26-bed critically ill patient in our ward did not know Chinese medicine when he first arrived. He had never used traditional Chinese medicine before treatment and strongly requested antibiotic treatment after admission. But the test results showed that it was not a bacterial infection and no antibiotics were needed. The medical staff patiently explained and conducted psychological counseling, formulated a treatment plan for traditional Chinese medicine, and adjusted the prescription in time according to the symptoms, tongue coating, and pulse changes of the patient, and often adjusted the traditional Chinese medicine to feed the patient. With the efforts of the medical staff, the patient's condition improved quickly, and his attitude towards taking Chinese medicine has also changed greatly. He actively asked the doctor to prescribe Chinese medicine and take it on time. After the patient was discharged from the hospital, a pennant was specially made for medical staff.

In the face of illness, doctors should show love, care for patients, relieve patients' emotions, and fill in things that medical technology cannot do.

I am deeply obsessed with this ancient science

Q: Your mother is also a Chinese medicine doctor, how does this affect your medical treatment?

Huang Luqi: Wuyuan, my hometown in Jiangxi, is one of the birthplaces of the Xin'an School of Medicine. This Chinese medicine school has a profound influence on the evolution of the theory of Chinese medicine during the Ming and Qing Dynasties. The mother is the heir of the Xin'an School of Medicine and a famous local Chinese medicine doctor in her hometown. When I was playing in my mother ’s clinic as a child, the most commonly used toys were “prescription papers”, and my favorite “snacks” were yeast tablets. I would often learn the “prescription” of my mother. The county town where my home is located is not big. When I follow my mother on the street, everyone calls her mother "Dr. Jin". The patient comes to the house to see a doctor. No matter what the mother is busy with, she will immediately put down her hand and concentrate on the consultation Sometimes to catch up with the meal, the mother also invites the patient to eat together. At that time, I felt that the doctor was very noble, and I was proud that my mother was a Chinese medicine doctor. It can be said that her "li-de and benevolence" that she taught by example always accompanied me.

Question: You have successively succeeded Mr. Le Chongxi, Academician Lou Zhicen, Mr. Cheng Jingrong, successors of Tongrentang. How much influence do these people have on you?

Huang Luqi: My childhood dream was to be a scientist. When I filled out my voluntary application for the college entrance examination in 1985, my father wanted me to study architecture, because there was already a sister who studied medicine at home, so I filled in the major of architecture on the volunteer form. However, destiny chose to arrange for me to "subscribe to the mother industry", and I was accidentally transferred to the Chinese Medicine Department of Jiangxi University of Traditional Chinese Medicine. But I didn't regret it at the time. Architecture and medicine are a big part of people's livelihood, and they are closely related to the people.

Later, I successively taught Mr. Cheng Le Chongxi, Academician Lou Zhicen, Mr. Cheng Jingrong, and their academic spirit deeply influenced me. I remember when the graduate student re-examined, Mr. Le Chongxi patiently taught me to correct the southern accent, and taught me a lot of dining rules and etiquette. Mr. Lou Zhicen, who was the chairman of the Chinese Pharmaceutical Association, has always been rigorous in his learning. I remember a brother who contributed to the highest-level professional magazine in China at that time. The editor thought the article was very good, but the length was long. After the brother gave the manuscript to the man, the man commented "We can't cut enough to fit the shoes" and signed "Professor of Pharmacy Lou Zhicen", then returned to the editorial department, and the final paper was published. The exemplary role of the gentlemen made me firmly determined to make some achievements in the field of Chinese medicine, and since then I have embarked on the road of traditional Chinese medicine.

Question: Along the way, do you have your own idol?

Huang Luqi: Li Shizhen is my idol. For so many years, I have regarded Li Shizhen as a model for learning. His spirit of knowledge, in-depth practice, adherence to truth, and medicine have always inspired and inspired me. During my PhD study at the Peking University School of Medicine, I went to Guangdong, Guangxi, Yunnan, and Guizhou for a field trip to investigate the medicinal plants of the genus Trichosanthes. Once, when I was doing a field survey in Guizhou, the car broke down on the road, and I walked alone along the road in the moonlight all night. At that time, the traffic was very inconvenient. From Kunming to Xishuangbanna, it took a week on the road, and the car also frequently appeared. The situation was often "uphill" and "downhill". Whenever I'm particularly tired, I think of Li Shizhen's perseverance when he tastes the herbs and the efficacy, and I have the courage to go on.

Question: In the eyes of some people, studying medicine is boring. What supports you in researching Chinese medicine?

Huang Luqi: It is love. I love Chinese medicine and am interested in it. During my studies, I was deeply shocked by the profoundness of traditional Chinese medicine, and fell in love with this ancient science.

Because of my love, I am not afraid of suffering. In 2011, the State Administration of Traditional Chinese Medicine launched the fourth national survey of traditional Chinese medicine resources, which was a "big picture" of the existing Chinese traditional medicine resources after nearly 30 years. In the past three years, as the leader of the expert group, I led the resource census team from all over the country to traverse the mountains, cross the mountains and the mountains, and traveled through more than 70 census pilot counties. Almost half of the time I worked with Chinese medicine in the wild. After the census, the basic status quo of domestic Chinese medicine resources has been proved. Recently we have also launched an overseas drug search program, which plans to find new drugs overseas and add them to the treasure trove of traditional Chinese medicine.

Because of my interest, I would like to devote all my energy. Before conducting taxonomic research on the Genus Aronia, I found that traditional biopharmaceutical techniques and methods could not be solved well. After more than 20 years of continuous and in-depth research, I introduced molecular biology techniques and established a new method for the identification of Chinese herbal medicines.

It can be said that without love, I cannot go through more than 70 census sites, nor will I put forward the concept of "molecular pharmacology". In any industry, you must devote yourself wholeheartedly, whether you want to focus on your heart, or whether you want to devote yourself to abandoning sleep and forgetting food, and only then can you achieve results. I do n’t think I ’m superior. I ’m a bit stupid, but I ’m sure I will find out where I am going.

If a person has lofty ideals and beliefs, he will not be destroyed by honor. My ideal and goal is "Sian Ji Qi Huang" to make more and better medicines for the people.

The thinking mode of TCM syndrome differentiation contains profound philosophical thoughts of the Chinese nation

Question: Today, how can we promote the modernization of Chinese medicine?

Huang Luqi: Traditional Chinese medicine is a treasure of ancient Chinese science and a key to unlocking Chinese civilization. To promote the modernization of traditional Chinese medicine, we must first have the cultural confidence to inherit traditional Chinese medicine and fully respect the historical status of traditional Chinese medicine. Starting from the written "Shen Nong's Materia Medica", traditional Chinese medicine is always absorbing the advanced technical methods at that time, and the understanding of drugs is also deepening. It should be noted that the “modernization” of Chinese medicine is a process that has not been interrupted for thousands of years. At present, in the modernization of traditional Chinese medicine, from the efficacy theory and original theory, to the matching technology of traditional Chinese medicine prescriptions, the effects of the body, etc., the core and basic entry point is clinical efficacy.

Question: In the prevention and treatment of epidemics, why emphasize the need to find high-level evidence-based evidence of the efficacy of Chinese medicine?

Huang Luqi: At present, the mainstream model of medical knowledge and practice in the world is the evidence-based medicine model with scientific evidence as the core, and clinical evidence has become the main basis for evaluating the effectiveness and safety of medical treatment measures. In March of last year, the China Center for Evidence-Based Medicine was inaugurated at the Chinese Academy of Chinese Medical Sciences, demonstrating our self-confidence and demeanour in picking up modern weapons to confirm the credibility of Chinese medicine.

Evidence-based medicine has a deep cultural foundation in China. "Medical Saint" Zhang Zhongjing collected and screened a large amount of clinical evidence on the basis of ancient medical records, verified the effect of the predecessors' prescriptions, integrated the treatment of syndrome differentiation with the theory of prescriptions, and wrote "Treatise on Febrile Diseases", which established the evidence-based research system of Chinese medicine The cornerstone is a true portrayal of ancient evidence-based research. The founder of evidence-based medicine, Sakot, said that the inspiration for the concept of "evidence-based medicine" came from the use of "examination" in the Qianlong period of the Qing Dynasty, which was to use evidence to study and explain ancient books. Combining evidence-based medicine with the characteristics of traditional Chinese medicine and applying it to clinical practice can not only greatly improve the level of clinical diagnosis and treatment, prove the value of traditional Chinese medicine, but also provide "tickets" for traditional Chinese medicine to enter the international stage.

Q: How do you view the relationship between Chinese medicine and Western medicine?

Huang Luqi: Culture influences the origin and development of medicine. Traditional Chinese medicine is different from Western modern medicine in concept. Traditional Chinese medicine is rooted in China ’s excellent traditional culture, adhering to the core values ​​of China ’s excellent traditional culture such as “health of man and nature” and “Dao law and nature”. Based on the profound philosophical thoughts of the Chinese nation, medical ethics has drawn on the concepts of "benevolence" and "rites" in Confucian culture. It is under the influence of these ideologies that TCM is not only inclusive. It not only excludes Western medicine, but also insists on equal emphasis on Chinese and Western medicine, advocates the integration of medicine, and guarantees that Chinese medicine and Western medicine enjoy equal development rights. I believe that Chinese medicine and Western medicine are both important components of China's health system, and the combination of the two can make greater contributions to the people's health. (Reporter Zhang Shengjun Zhang Zijian)