iPS cells Clinical study of knee joint cartilage transplantation Kyoto University application November 27 12:43

A group of Kyoto University has applied to the country for a clinical research plan to create a cartilage tissue from iPS cells and transplant it to a patient with damaged knee joint cartilage.

The cartilage tissue at the knee joint hardly regenerates if it is injured.

Currently, there is a method of surgically removing and transplanting cells of cartilage from other healthy parts such as elbows, but the burden on patients is becoming a problem.

A group of professors Noriyuki Tsumaki of Kyoto University's iPS Cell Research Institute made a plan for a clinical study to make cartilage tissue from human iPS cells and transplant it to patients with damaged knee joint cartilage on the 7th of this month. I made it clear that I applied.

The plan is to perform an operation to transplant the cartilage tissue made from iPS cells into the patient's knee, and confirm the safety and effectiveness, so that the joint can be moved again while reducing the burden on the patient. Aim.

The review is expected to start as early as next month, and the group will begin transplanting patients to the patient after next year if the national approval is obtained.

Transplantation of cells and tissues made from iPS cells was performed at Kyoto University, in which cells that become the source of nerves were transplanted into the brains of Parkinson's disease patients, and teams such as RIKEN in Kobe City The eye retinal tissue, Osaka University, is conducting clinical research to transplant the eye cornea tissue.