A Canadian study found that a compound found in avocados can be helpful in preventing type 2 diabetes, which accounts for the majority of cases, when the body becomes insulin-resistant or loses the ability to produce enough insulin from the pancreas, which is necessary to maintain levels of Blood glucose levels are healthy, but the study by the University of Guelph, Canada, was published in the latest issue of Molecular Nutrition & Food Research, which found that avocatine B in fruit could block this trait. Characteristic of diabetes.
"Insulin resistance in type 2 diabetes occurs when mitochondria cannot burn fatty acids by oxidation enough," Dr. Nawaz Ahmed, lead researcher in the study, said in a report published yesterday by Medical News Today. Or that oxidation is incomplete, and in the study of mice before the transition to clinical trials, we found that the compound in avocado works against the oxidation of incomplete fatty acids in the mitochondria by muscles and And Lin ».
During the study, Dr. Nawaz and his companions fed the mice to a high-fat diet for 8 weeks to promote obesity and insulin resistance, and then added the avacado compound to the rats' diet for the next 5 weeks.At the end of the 13 weeks, the mice who gained the weight Slower than their counterparts, insulin sensitivity has increased.
In a clinical study that followed, the researchers investigated the effects of dietary supplements containing the compound, coupled with a 60-day average Western diet.
The researchers tested taking either 50 milligrams (mg) or 200 mg.
The team is now designing clinical trials to assess the efficacy of the compound alone in humans, and they have already received CMA approval to sell it in powder or pills, possibly by next year, Dr. Nawaz said.