The world's first human iPS cells from multiple organs at the same time Tokyo Medical and Dental University, September 26, 4:53
A research group at Tokyo Medical and Dental University announced that it was the first in the world to succeed in simultaneously creating multiple organs such as the viable organ from human iPS cells. Similar to the environment in the human body, it is expected to lead to future transplantation with a new method that simultaneously creates multiple intertwined organs.
The research was published in the British scientific journal Nature by a group of Professor Takanori Takebe from Tokyo Medical and Dental University.
First, the group cultured human iPS cells, which become various tissues of the body, up to the stage before becoming digestive organs such as stomach and intestine.
And, among them, the cells that changed relatively to the upper part close to the stomach and the cells that changed to the lower part close to the small intestine were cultured, and the liver and pancreas, and the bile duct connecting them were successfully created at the same time. about it.
The total size is about one centimeter, which is almost the same as that of a human fetus for about a month after fertilization, and functions to a certain extent, such as fluid flowing from the liver to other organs. It is said that it was able to confirm that there is.
It is the first time that multiple infectious organs have been created simultaneously from iPS cells, and the research group will be able to transplant and use it for treatment if blood vessels can be cultured at the same time. The
Professor Takebe says, “It is completely different from the conventional method of creating a single organ. There are many challenges, but I would like to advance my research to a state where transplantation is possible within 10 years.”