Tobacco alters the immune system even after quitting. The study has analyzed the impact of 136 environmental factors on the variability of immune responses in a thousand volunteer individuals.

The research was carried out on 1,000 healthy volunteers (one hundred women and one hundred men for each decade, between 20 and 69 years of age) Age, sex, smoking habit, body mass index, genetic variations and cytomegalovirus infection, among others, were determined. Among the environmental factors studied, it was demonstrated that smoking has the greatest influence on immune responses.