The Prosecutor's Office of the National Court investigates the possible health responsibility for the consumption of Nolotil. In Spain it is one of the most prescribed analgesics for intense pain that does not subside with the ingestion of Paracetamol.
In some countries such as the United States, the United Kingdom, and Ireland, this drug is banned due to a rare side effect that can lead to an immune disorder called agranulocytosis. This complication is rare and is related to a greater genetic predisposition in the Anglo-Saxon population.