Physiologically, addictive behavior causes neuroadaptive changes that make people gradually dependent on it. From a psychological point of view, the causes of addiction often involve emotional and psychological stress.

Smoking addiction can lead to lesions of other systems throughout the human body, and damage to white matter structure is one of the core changes in the pathological changes of the smoker's brain. Study of changes in white matter function in smokers is of great significance for revealing the neural mechanism of smoking addiction. The team of Professor Zhang Xiaochu of the University of Science and Technology of China revealed the abnormalities of the white matter functional network of smokers.