In China, about 1 to 2 people per 100,000 people are sick with generalized pustular psoriasis. The disease can recur or be persistent, accompanied by liver and kidney damage, and can be life-threatening due to secondary infection and organ failure.

There are many causes of the disease, and drugs, infections and genetic mutations may all be the triggers. Innovative targeted biological agents for the treatment of adults with generalized Pustular Psoriasis have been prescribed for the first time.