A study published in the journal Nature Medicineoffers insights into a new drug that could make it easier to treat cannabis addiction. AEF0117, a drug that targets a mechanism that inhibits a subset of the molecular pathways activated by the cannabinoid receptor 1 (CB1) Data from preclinical studies showed that the drug was able to inhibit the behavioral effects of THC without altering normal behavior or physiological activities in mice and primates.
It also reports the results of two phase 1 clinical trials conducted in 64 healthy volunteers where it was found to be safe and well-tolerated.