A bottle of NMN elixir that has been fired for tens of thousands of yuan, the ex-factory price is less than 100 yuan

　　China-Singapore Jingwei, July 24th (Lin Wansi and Yan Shuxin) "NMN products sold through e-commerce channels range from a few thousand yuan to several thousand yuan, and a bottle of NMN products from several thousand yuan to tens of thousands of yuan on the market is a closed channel. However, the ex-factory price of NMN products is not high.” Recently, an NMN product foundry told Sino-Singapore Jingwei that the processing price of NMN products produced by their factory is only about 100 yuan.

　　In recent years, NMN is undoubtedly the hottest "upstart" in the health care product industry.

Along with the controversy, NMN products "revived" after being approved for the filing of new cosmetic raw materials.

　　However, it is still unclear whether NMN products have the effect of "rejuvenating the old and rejuvenating". Due to the prohibition of domestic supervision, domestic consumers who want to buy NMN for consumption can only purchase imported NMN through cross-border e-commerce and other channels.

Many manufacturers use this to "gold-plate" through overseas production and OEM. The price of NMN products is tens of thousands of yuan, while the industry OEM price is only more than 100 yuan. What kind of industrial chain is behind this?

The price of a 300 yuan product is 20 times that of the original powder

　　A reporter from China-Singapore Jingwei saw on domestic e-commerce platforms that NMN's products range in price from 60 to 20,000 yuan.

Sino-Singapore Jingwei searched on the e-commerce platform and found that

　　The price of the product is high and the profit is not low.

According to the research report "NMN Industry Ten Questions and Ten Answers: Rapidly Expanding Anti-aging Health Products" released by CITIC Securities in 2020, the gross profit rate of NMN health care products is between 70% and 80%, and the long-term gross profit rate of health care products leader Tomson By-health At 65%-70%.

　　In July 2020, the NMN products of Doctor's Best, an international brand under the A-share listed company Jindawei, have been put on the market.

According to its disclosure, the raw materials are produced by the subsidiary Inner Mongolia Pharmaceutical, and the finished products are produced in the United States.

Taking Jindawei's NMN products as an example, Sino-Singapore Jingwei consulted as a consumer. The sales staff of the brand store told Sino-Singapore Jingwei that NMN has certain auxiliary anti-aging, DNA repair, regulation of diabetes, and regulation of cardiovascular problems. , hangover and protect liver and protect eyesight and hearing.

After NMN is ingested by the human body, it will be converted into NAD+ (coenzyme I, the full name of nicotinamide adenine dinucleotide). NAD+ itself is the maintenance of metabolism and energy production in the human body. It has no side effects and can be taken for a long time.

　　The salesperson said that the product is a dietary supplement and there is no concept of a course of treatment.

Depending on the constitution of the user, the time for the effect of the product to occur is also different.

Sensitive physiques showed significant improvement in about a week, and the first manifestation was that their sleep conditions gradually improved.

Normal physique will feel improvement in physical function in about two to three weeks.

　　The salesperson recommended an NMN product with a price of 1799 yuan according to the age of the reporter from Sino-Singapore Jingwei. According to the recommendation of taking 2 capsules a day, the cost of taking it for two weeks is about 900 yuan.

　　Another popular Japanese brand ATRITENA's NMN product sales customer service staff recommended a 2850 yuan product to Sino-Singapore Jingwei, claiming that taking 1 to 2 bottles can see the effect, such as better sleep and better spirit.

According to the salesperson's suggestion, it takes about 5,000 yuan to "have a certain effect."

　　The above two products are converted, the former contains 300 mg of NMN per two capsules, the price per mg of NMN is about 0.2 yuan, and the price

the latter contains 200 mg of NMN per capsule, and each mg of NMN is 0.24 yuan,

　　However, Sino-Singapore Jingwei also saw the sale of NMN original powder on the e-commerce platform.

Sino-Singapore Jingwei consulted and purchased NMN raw powder as an individual consumer. The merchant said that 90% of imported brand raw materials are domestically exported.

10 grams of NMN original powder is 178 yuan, which is equivalent to

.

However, the store sales said that these products are sold as raw materials or used for scientific research and experiments.

　　It is understood that raw materials such as pharmaceutical intermediates are not edible, only for export, scientific research and laboratory use, non-medicinal and non-edible.

However, the merchant proposed to add a reporter’s WeChat, and posted a message on WeChat that the original powder can be taken with water or under the tongue, and activators such as grape seeds, betaine, coenzyme Q10, PQQ, lipoic acid, etc. , can assist absorption.

　　Sino-Singapore Jingwei found that

　　In fact, as NMN products continue to mature, raw material prices also decline.

According to the "2021 China β-nicotinamide mononucleotide (NMN) industry overview" released by the Head Leopard Research Institute, the price per kilogram of NMN raw materials has dropped from 160,000 yuan per kilogram before maturity to 3,000 yuan after maturity. The comprehensive cost per kilogram of NMN is 2,200 to 2,500 yuan, and the profit margin of NMN raw materials is 16.7% to 26.7%.

　　According to public information, the full name of NMN is "β-nicotinamide mononucleotide", which is a naturally occurring biologically active nucleotide.

It is an inherent substance in the human body and is also abundant in some fruits and vegetables.

Because nicotinamide belongs to vitamin B3, NMN belongs to the category of vitamin B derivatives. It is widely involved in many biochemical reactions in the human body and is closely related to immunity and metabolism.

In January 2021, the State Administration for Market Regulation issued the "Letter on Investigating the Illegal Operation of "Elixir", which clearly pointed out that at present, NMN has not obtained licenses for medicines, health food, food additives and new food raw materials in China, and NMN cannot be used as a Food production and operation.

　　The reason why NMN can be sold on e-commerce platforms is mainly because as a derivative of the vitamin B family, it has been included in the "positive list" of the "Announcement on the Announcement of the List of Cross-border E-commerce Retail Imported Commodities", which is indirectly NMN. Inbound sales provide the possibility, and the products are expensive. From the perspective of import channels, the brands of many products are from Europe, America and Japan.

Overseas production OEM "gold-plated" midstream profit margin exceeds 80%

　　Although NMN does not have a legal status in China, many foundries can still

　　Sino-Singapore Jingwei noticed that there are many manufacturers on the wholesale website that can provide one-stop services from production to OEM.

Most of their raw materials are sourced from mainland China. After β-nicotinamide mononucleotide powder or capsules have obtained the record certificate of export food production enterprises, they are processed into semi-finished products in mainland China, and then exported to the United States, Japan, Canada and other countries to make Finished products, complete packaging, and then transported to bonded warehouses; some foundries directly transport raw materials to other countries for production.

　　After the transaction, the product is delivered directly from the bonded warehouse to the buyer, turning it into an imported NMN product.

Many manufacturers said that "all are legal and formal customs declaration and tax payment".

　　Sino-Singapore Jingwei contacted a foundry in Guangdong in the name of the company, which said that it is recommended to produce OEM in Hong Kong, and it can be delivered in 25 to 30 days.

Other regions are also available, but the transportation cost and cycle will increase, and more uncontrollable factors will be added.

He said that according to the above operation link, it is equivalent to a Hong Kong product. If you want to OEM, you need to register the company's main body and trademark in Hong Kong.

If the customer does not have one, the foundry also has a trademark that the customer can use for free and design the packaging.

　　The foundry sent a price list for OEM processing of NMN products. It shows that a NMN capsule product with an NMN content of 300 mg, a bottle of 60 capsules, and 5,000 bottles can be processed at a price of only 104 yuan per bottle; NMN with a NMN content of 200 mg. Capsule products, a bottle of 60 capsules, the price of processing from 5000 bottles is only 81 yuan / bottle.

Compared with NMN products that sell for thousands on the Internet, the price of foundry products with the same NMN content is only one tenth of that.

　　According to the "2021 China β-nicotinamide mononucleotide (NMN) industry overview" released by the Toubao Research Institute, according to the cost and selling price of the NMN industry chain, the midstream profit of the NMN industry chain is the highest, at about 83.3%.

　　Another OEM with production in the United States told Sino-Singapore Jingwei that the factory purchases raw materials in China, which is more cost-effective.

He introduced that the United States mainly uses the whole enzyme method to prepare, and it can be delivered in about one and a half months. In Japan, the fermentation method is used to prepare, the cycle is long, it takes about three months to deliver, and the cost is high.

The delivery price of a bottle in the United States is more than 100 yuan, and the product produced in Japan costs 300 to 400 yuan. The final product is almost the same. Therefore, it is recommended to choose a factory in the United States to produce and OEM, and then deliver it to the customer's bonded warehouse in Hong Kong.

　　"If you want to do private domain traffic, you can use direct mail from Hong Kong in the form of overseas purchasing, and send one piece on behalf of others," said the foundry.

The foundry sent to Sino-Singapore Jingwei the US-imported NMN products and price list that the factory found, and the foundry price of a product with a NMN content of 300 mg was 170 yuan/bottle (excluding warehousing fees), while the same on the e-commerce platform For products with the same packaging, the same dosage (60 capsules per bottle), and the same NMN content, the price is as high as 3,543 yuan per bottle, and the retail price is 20 times the OEM price.

A new breakthrough in NMN regulation, how far is it from health care products?

　　Liu Nan, a researcher at the Interdisciplinary Research Center of Biology and Chemistry of the Chinese Academy of Sciences, has long been committed to anti-aging research. In an interview with the media this year, he said that the decrease in the level of NAD+ in the human body is one of the main causes of aging. NMN can be activated by supplementing NAD+, thereby starting to delay aging.

It is understood that NMN is the precursor of NAD+, which plays an important role in various cellular metabolic reactions and is closely related to human aging.

　　In fact, there is still controversy about whether the anti-aging and life-extending effects of NMN have clinical significance in humans.

　　In December 2021, the State Administration for Market Regulation stated in the "Reply to Recommendation No. 1067 of the Fourth Session of the Thirteenth National People's Congress" (hereinafter referred to as the "Reply") that at

.

NMN and related products have not yet been registered as health food in my country. The conditions for NMN to be used as a raw material for health food are not yet mature, and further monitoring and research are needed.

　　The "Reply" also stated that for NMN, my country is currently in the research stage, and the China National Institute of Standardization and the China Academy of Inspection and Quarantine have the ability to carry out NMN-related research, including the history of NMN use at home and abroad, safety, functionality and function claims Wait.

　　Regulatory oversight of NMN products is also increasing.

In January 2021, the State Administration for Market Regulation issued the "Letter on Investigating the Illegal Operation of "Elixir", which clarifies that NMN cannot be produced and traded as food in my country, and requires a comprehensive investigation.

At that time, NMN concept stocks suddenly became cold.

　　In the first half of this year, NMN once again attracted widespread attention.

Market discussions point to the approval of NMN as a cosmetic raw material.

The filing company is Yuyao Lifespan Health Technology Co., Ltd., which is the Gene Harbor β-NMN raw material factory. The filing date is January 24 and June 29, 2022.

　　In addition, Kangying Redberry (Zhongshan) Biotechnology Co., Ltd. and Shenzhen Weiqi Pharmaceutical Research and Development Co., Ltd. were approved by NMN as a cosmetic raw material in March and April this year, respectively.

　　Many experts said that the approval as a cosmetic raw material this time means that the supervision in related fields is being relaxed, and it can be used in cosmetics at present, and it is likely to be approved for dietary supplements in the next stage.

　　It remains to be seen where NMN products ultimately go.

(Sino-Singapore Jingwei APP)

(The opinions in this article are for reference only and do not constitute investment advice. Investment is risky, and you need to be cautious when entering the market.)