The first topic of the evening will be household finances, a debate that kicks off with a duel between Prime Minister Ulf Kristersson (M) and opposition leader Magdalena Andersson (S).
"With record inflation and rising prices making it much more expensive to live in Sweden, it was obvious to let Ulf Kristersson and Magdalena Andersson meet in a duel over household finances," says Camilla Kvartoft, who is leading the debate together with Anders Holmberg.
"I think viewers are very interested in how they want to support the families who have the hardest time making ends meet. And what policy measures could help bring down inflation.
Cultural debate
The structure of the party leader debate is familiar. Each topic starts with a duel between two party leaders before the others are admitted.
After household finances, culture will be debated, focusing on how much influence politicians should actually have over culture. Duels are made by Sweden Democrats party leader Jimmie Åkesson and Green Party Märta Stenevi.
"As far as I can remember, it has been a very long time since the party leaders were allowed to debate cultural policy. The issue has heated up since local politicians stopped drag queen artists from reading stories to children in libraries. Should politicians who distribute cultural money be allowed to have views on which exhibitions and plays they put on? It will be interesting to hear the party leaders discuss what arm's length distance from culture really means, says Camilla Kvartoft.
Finishing with integration
The second hour of the debate begins with a climate debate between the Christian Democrats' Ebba Busch and the Center Party's new party leader Muharrem Demirok, who is making his first party leader debate in Agenda.
The evening then ends with a well-debated topic: integration. The Liberals' Johan Pehrson and the Left Party's Nooshi Dadgostar meet in a duel, after which the ensuing debate will focus on the Tidö parties' proposal for a "demands-based integration policy" and whether there is anything that can improve integration in Sweden.