Acute diarrheal infection caused by the absorption of food or water contaminated with bacteria, cholera is on the rise, particularly in Africa, the World Health Organization recently warned.
The victim from Benoni, about 40 km from Johannesburg, died in hospital on Sunday, the health ministry said in a statement.
The tests carried out later proved positive for cholera.
A total of five cases have been recorded in the country since the beginning of the month.
The last epidemic in South Africa dates back to 2008-2009, with some 12,000 recorded cases.
The disease was then rampant in neighboring Zimbabwe.
This time, the center of the epidemic is in Malawi, a country in southern Africa which is experiencing a deadly wave and which is in lack of vaccines.
At least 1,400 people have died out of the 45,000 cases reported since March 2022 in this country among the poorest in the world, according to the UN.
Cases have also been recorded in Mozambique and Zimbabwe.
© 2023 AFP