China News Service, Guangzhou, March 6th (Cai Minjie and He Yuhang) "I recommend that the elderly, especially the elderly, get vaccinated as soon as possible." Liang Xiaofeng, vice president of the Chinese Preventive Medicine Association, said in Guangzhou on the 5th that Omick The Rong variant strain is indeed relatively strong in transmission, and the risk to the elderly is greater.

Judging from the experience and lessons of surrounding cities, he recommends that the elderly in cities with a high proportion of the elderly population be vaccinated against the new crown as soon as possible.

  On the same day, a seminar on the implementation of sequential booster immunization for the new coronavirus vaccine was held in Guangzhou.

Experts from the field of public health and the vaccine industry conducted exchanges and discussions on the interpretation of the "Implementation Plan for Sequential Enhanced Immunization of New Coronavirus Vaccines", the clinical research of new coronavirus vaccines with different technical routes, and the evaluation of enhanced immunization effects.

  At present, many provinces and cities have successively started the sequential booster vaccination of the new coronavirus vaccine, and some cities in Guangdong Province have also carried out sequential booster immunization work.

  Sequential booster immunization refers to a strategy that uses vaccines with different technical routes from basic immunization, and carries out booster immunizations at certain time intervals and doses, mainly to further improve the preventive effect of vaccines and reduce the risk of adverse reactions occur.

  For conventional and easy-to-treat viruses or diseases, vaccines with a single technical route are generally sufficient, but for viruses with strong variability and difficulty to deal with such as the new coronavirus, sequential booster immunization can be used.

  Liang Xiaofeng said that the National Health and Health Commission has begun to deploy sequential booster immunization. Both homologous booster immunization and sequential booster immunization can further improve the effect of immunization, and it is of great practical significance to carry out booster immunization work.

  Yu Wenzhou, chief physician of the Immunization Planning Center of the Chinese Center for Disease Control and Prevention, said in a video on the same day that vaccines of different technical routes each have different immunity-inducing properties, and sequential immunization of two or more different types of vaccines in time may overcome the The insufficiency of a single vaccine may induce a comprehensive protective immunity, so as to obtain an ideal immune effect.

  "At present, there is evidence that inactivated vaccines and adenovirus vector vaccines of the new coronavirus need to be boosted." Yu Wenzhou said that sequential immunization can improve the level of humoral immune response, especially the level of cellular immune response.

Sequential immunization has been used in the development of vaccines for HIV, HCV, HSV and HBV against corresponding infectious diseases.

  "With the large-scale emergence of virus mutant strains around the world, it is inevitable for the new crown vaccine to have mixed vaccination in the future, and the sequential immunization plan is conducive to dealing with virus mutation and improving the control of the epidemic." Yu Wenzhou said, sequential immunization plan Immunization will provide a more flexible opportunity to receive a "boost" program, helping to accelerate global Covid-19 vaccination.

  Zheng Huizhen, chief expert on disease control of Guangdong Preventive Medicine Association, made a report on the "Guangdong Province New Crown Vaccine Sequential Enhanced Immunization Program", and introduced the relevant situation of Guangdong Province's new crown virus vaccination. Safety and efficacy of sequential booster immunization.

  Under the current background of the continuous development of the global new crown pneumonia epidemic, the spread of new coronavirus mutant strains is accelerating, and Guangdong Province is still facing greater pressure to "prevent import from abroad and prevent rebound from within".

Experts at the meeting said that vaccination against the new coronavirus is still the most effective, safe and economical measure to prevent and control the new coronary pneumonia. Strengthening immunization is of great significance to protect susceptible groups and effectively curb the spread of the epidemic. It is recommended to protect the elderly and high-risk groups as soon as possible. Boost immunization.

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