Macron promises to work for a stronger France and Europe in the face of an "accumulation of crises".
"That is why I ask for your confidence for another term as President of the Republic," Macron wrote in a letter addressed to the country, which was published on Thursday evening.
Has been postponed
Macron's message has been postponed due to the war in Ukraine, when the 44-year-old French president took a prominent role in the diplomatic talks.
On Thursday, he spoke again by telephone with Russian President Vladimir Putin, urging him to stop the invasion.
The last day for aspiring candidates to register their participation in the battle for the presidency in France is on Friday.
Opinion polls show that Macron is in the lead ahead of the election, which will take place in two rounds, on 10 and 24 April.
Due to the war in Ukraine, domestic politics have become increasingly obscured, to the detriment of the other candidates.