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December 20, 2021 It is the latest addition to the vaccines approved in the EU, and joins Pfizer-BioNTech, Moderna, AstraZeneca and Johnson & Johnson.



The basic principle of the Novavax vaccine uses recombinant proteins, different from those with mRna (Pfizer / Biontech and Moderna) and with respect to those with viral vector (Astrazeneca and Johnson & Johnson). The drug uses pathogen proteins - antigens - to stimulate the immune system. 



All vaccines currently available against Covid and their characteristics:



Novavax, the latest arrival.


The technique has been in use for some decades on other diseases: meningitis, hepatitis b and papilloma virus: it has been tested on over 45,000 people, demonstrating - according to what documents pharmaceutical company - a

89.7% efficacy.



Pfizer


Comirnaty, the Pfizer-Biontech vaccine, was the first to be authorized for use in Europe on December 21, 2020.



It is

94.6% effective

starting 7 days after the second dose. It is administered through two injections, at least 21 days apart and should be stored in the freezer at a temperature between -90 ° C and -60 ° C.


It contains a molecule called messenger Rna (mRna) with instructions for making a protein found on Sars-CoV-2, the virus responsible for Covid-19.



Moderna


Spikevax, the Moderna serum, like the previous one, is a messenger Rna. It was authorized by the EMA on January 6, 2021 and has a

93.6% efficacy

from 14 days after the administration of the second dose, which is injected 28 days after the first. It is stored in the freezer at a temperature between -25 ° C and -15 ° C and is stable between + 2 ° C and + 8 ° C for 30 days.



Astrazeneca


Vaxzevria, AstraZeneca's serum, authorized on January 30, 2021, unlike the previous two, is a viral vector vaccine, which uses a modified version of the chimpanzee's adenovirus - no longer able to replicate - as a vector to deliver instructions for the synthesis of Sars-CoV-2 "spike protein". It has an

efficacy of around 80%

15 days after the second dose (when this is injected) between 10 and 12 weeks after the first and - from the data released immediately after the trial - it has a coverage that is close to 100% on the most serious cases of the disease. It is stored in the refrigerator at a temperature between 2 ° C and 8 ° C.



Johnson & Johnson


Janssen of the Janssen vaccine (Johnson & Johnson) uses a human adenovirus (Ad26) as a viral vector. It is given in a single dose from 18 years of age. (With circular 21 April 2021, the ministry recommends a preferential use of the vaccine in people over the age of 60). It was authorized in Italy on March 12, 2021 and is

effective in severe forms that reaches 77

% after 14 days from administration and 85% after 28 days from administration.


It is stored in the freezer at a temperature between -25 ° C and -15 ° C.



It usually takes five to ten years to develop a vaccine.

For Sars-CoV-2, on the other hand, in less than a year we have gone from the discovery of the previously unknown pathogen, to the beginning of vaccinations, inaugurated in Europe from the Vax-day of December 27, 2020.