(Fighting New Coronary Pneumonia) Research shows that China's inactivated vaccine has an effective overall protection rate of 59% against the Delta strain
China News Service, Guangzhou, August 23 (Reporter Cai Minjie) Guangdong Nanshan Medical Innovation Research Institute said on the 23rd that the Guangzhou Center for Disease Control and Prevention, together with the team of Zhong Nanshan, an academician of the Chinese Academy of Engineering, and the team of Associate Professor Zhang Dingmei from the School of Public Health, Sun Yat-sen University, are based in Guangzhou this year. Cases and close contacts of the new crown epidemic from May to June are the subjects of study. Through a case-control study with a test-negative design, the protective effect of China's domestic new crown virus vaccine against the Delta variant strain is estimated.
The above real-world studies show that the overall protection rate of the two domestic inactivated vaccines in China is 59%, the protection effect for the prevention of moderate new coronary pneumonia can reach 70.2%, and the protection effect for severe cases is 100% (due to the small sample size of severe cases) , This result will overestimate the protective effect of severe illness).
In addition, the protective effect of the vaccine is slightly higher in the 40 to 59-year-old population and the female population.
The paper was recently published in the internationally renowned journal "Emerging Microbes & Infections" focusing on the field of emerging infections.
The new crown pneumonia epidemic is still a worldwide pandemic. In order to curb its spread, a variety of new coronavirus vaccines have been developed around the world, including inactivated vaccines, recombinant protein vaccines, adenovirus vector vaccines, DNA vaccines and RNA vaccines.
These vaccines have achieved certain vaccine efficacy in clinical trials.
However, since previous studies have confirmed that the effectiveness of the new crown vaccine against newly emerging variant strains has decreased, people are very worried about whether these mutations mean that the new crown vaccine currently in use has become invalid.
The research of Zhong Nanshan and his team is the first internationally reported real-world study of the protective effect of Chinese domestic vaccine on the Delta variant strain.
The study found that China-made inactivated vaccines are effective against Delta variants. Two complete doses of inactivated vaccines have an overall protective effect of 59.0% against Delta variants, and the protection rate against moderate symptoms is 70.2%.
The World Health Organization has previously proposed a minimum protection effect of 50%.
Therefore, the domestic inactivated vaccine is still effective against the Delta mutant strain.
Studies have found that the protective effect of inactivated vaccines is slightly higher in people aged 40 to 59 years and in female groups. Previously, the coverage of China's new crown vaccine was mainly for people aged 18 to 59 years old.
The findings of the study suggest that the coverage of vaccination should be further expanded, the population vaccination rate should be continuously increased, and the vaccination of young people and children under 18 and the elderly over 60 should be promoted.
The study also found that only one dose of inactivated vaccine can not produce effective protective effect, and the second dose of inactivated vaccine can produce better protective effect 2 weeks after vaccination.
It is recommended that the recipients complete the complete two-dose vaccination in accordance with the regular process, and establish effective herd immunity as soon as possible.
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