"Huoyan" discriminates "yin and yang" black technology highest daily inspection of 2 million nucleic acid samples

  ◎Reporter Jin Feng

  In the white inflatable "greenhouses", the staff are operating the nucleic acid extraction and purification instrument and the automatic cupping processing system. There is only one goal, and the results will be identified as soon as possible from the nucleic acid test samples collected from all over Nanjing.

This is no ordinary "greenhouse".

  At 8 pm on July 28, a reporter from Science and Technology Daily walked into the Nanjing "Fire Eye" laboratory in Nanjing International Expo Center. The 12 negative pressure hard air capsules and 15 negative pressure soft air capsules have occupied an area of ​​8,000 square meters. space.

  On the evening of the 26th, after overnight construction and commissioning, the Nanjing "Huoyan" laboratory was completed. At present, the laboratory has been officially put into use.

"The daily detection throughput can reach 200,000 single tubes. If 10 mixed 1 mixed collection technology is used, a maximum of 2 million nucleic acid samples can be detected per day." Chen Wurong, director of production support at BGI Gene Delivery Center, told a reporter from Science and Technology Daily.

  The reporter saw on the scene that the "Huoyan" laboratory was surrounded by an air arch structure, with the outermost layer wrapped by a thick plastic layer.

  "The air film version of the "Huoyan" laboratory uses flame-retardant, wear-resistant, and highly stable PVC materials as the main building materials. The air arch structure is formed by a double-layer air film to provide a negative pressure environment, which meets the requirements of the BSL-2 laboratory. Requirements: At the same time, it has a high volume compression ratio, can be folded and disassembled, and can be transported by air cargo after packaging, which can realize flexible site selection, rapid transportation, rapid layout, rapid construction, and rapid start-up." Chen Wurong said.

  In order to improve the efficiency of large-scale nucleic acid detection, the "Huoyan" laboratory is also equipped with a variety of automated anti-epidemic black technologies independently developed by MGI, which greatly improves the detection efficiency compared to manual operations.

  "Among them, the MGISP-NE384 automatic nucleic acid extraction and purification instrument can effectively assist in the extraction of viral nucleic acids, with a single-machine daily detection throughput of up to 10,000 cases, which greatly accelerates the laboratory's detection process." Chen Wurong said.

  In addition, the MGISTP-7000 automatic sub-cup processing system in the air film cabin can complete the automatic sub-packing and information processing of 192 samples within 40 minutes.

Chen Wurong introduced: "It solves the most labor-intensive and infection risk sample packaging process in nucleic acid testing."

  The MGISP-960 high-throughput automated virus nucleic acid extraction equipment has passed the epidemic prevention and control verification in more than 50 countries around the world, and has powerful automated nucleic acid extraction functions and automated sequencing library preparation functions.

  The "Huoyan" laboratory was first born in Wuhan on February 5, 2020, with a detection throughput of 10,000 people per day, providing sufficient detection capabilities for Wuhan and surrounding cities.

  In the current round of the epidemic in Nanjing, under the guidance of the Nanjing Municipal Health Commission, Nanjing "Huoyan" laboratory was constructed by BGI and Nanjing Construction Management Group. After completion, Nanjing No. 1 Hospital was responsible for operation, and BGI provided technology. Support and jointly ensure the normal operation of the laboratory.

  Up to now, the "Huoyan" laboratory has been established in many major cities such as Beijing, Wuhan, Shenzhen, Tianjin, Shijiazhuang, and Guangzhou.

As the "China Business Card" for fighting the epidemic with science and technology, the "Huoyan" laboratory has also moved from China to the world. It has established more than 80 locations in nearly 30 countries and regions around the world, and has become the "outpost" for the international community to jointly respond to the new crown epidemic. Assist the prevention and control of the new crown epidemic and make positive contributions to the protection of public health in various countries and regions.