China News Service, Beijing, March 28. The "Female Nutrition and Reproductive Health Promotion Action" project kick-off meeting and consensus interpretation teacher training meeting hosted by the China Medical Education Association and the Reproductive Endocrinology Committee of the China Medical Education Association was held in Beijing on the 27th.

The project aims to pay attention to women’s nutrition and reproductive health. With the support of evidence-based medicine, it explores a set of effective methods and methods for publicity, education and guidance, and forms practical measures for the implementation of prenatal and postnatal care, and further guides all regions to comprehensively strengthen age-appropriate childbirth. The population's nutrition and health care work before pregnancy and pregnancy and childbirth promotes prenatal and postnatal care and improves the quality of the nation.

  The China Medical Education Association has organized experts from the Reproductive Endocrinology Committee to compile the "Chinese Expert Consensus on Reproductive Health and Multiple Micronutrient Supplements" based on full discussions, and will be published in the "China Practical Gynecology" in April this year. Journal of Obstetrics and Gynecology.

  The "Consensus" interpretation teacher training meeting is the second stage of the entire project. It invited Jia Wannian, vice president of China Medical Education Association, chairman of the Reproductive Endocrinology Committee of China Medical Education Association, and Peking Union Medical College Hospital Gynecological Endocrinology With Professor Yu Qi, Director of the Reproductive Center, Professor Wang Hua, Deputy Dean of Hunan Maternity and Child Health Hospital, Professor Zhang Yunshan, Director and Deputy Dean of the Reproductive Medicine Center of Tianjin Central Obstetrics and Gynecology Hospital, and other experts, focusing on the hot and difficult issues of the "Consensus" Share and exchange, standardize academic content, reflect scientificity, authority, advancement and practicality, and specify the direction of the tour topic.

  In the third phase of the project (April to August this year), the association will hold six online and offline combined "pre-pregnancy micronutrient supplement" tour series activities across the country to help Chinese reproductive departments and gynecologists understand reproductive health and The importance of multiple micronutrients promotes the content of the "Consensus" nationwide to promote standardized clinical diagnosis and treatment.

As a life science company focusing on nutrition and health, Bayer will cooperate with the China Medical Education Association to support the "consensus" national tour and content dissemination, to help the development of China's reproductive health, and to take care of the reproductive health of child-bearing couples of the right age.

  "Holding this project is a concrete action to implement the'Healthy China 2030' planning outline. The'Women Nutrition and Reproductive Health Promotion Action' project we launched today is put forward under the background that the national policy attaches great importance to the nutrition and health work during pregnancy and childbirth. Schedule." Jia Wannian, vice president of the China Medical Education Association, said at the meeting that the organization of this project is an effective measure to solve the current outstanding problems of women's health in my country, and it is also the responsibility of the association to assume social responsibility.

  Let incubation avoid the "trap" trap

  my country is a country with a high incidence of birth defects. Approximately 900,000 of the 16 million newborns are born with birth defects each year.

After the implementation of the “comprehensive two-child” policy, the number of second-children has increased significantly, and the proportion of older pregnant women has increased, which means that the risk of birth defects has also increased.

  With the awareness of birth defects and fertility and other issues, as well as concerns about the problem of pre-pregnancy nutritional imbalance, supplementation of a variety of micronutrients before pregnancy prevents birth defects and improves fertility evidence and recommendations continue to appear.

A large number of studies have proved that supplementing a variety of micronutrients before and during pregnancy is of great significance to the reproductive health and fetal development of family planning couples.

  "Reproductive health is closely related to nutrient supplementation. The lack of nutrients such as iron, mineral elements, and folic acid in the mother can cause infants to suffer from nutritional deficiencies, congenital diseases and other risks." Professor Yu Qi from Peking Union Medical College Hospital Gynecological Endocrinology and Reproductive Center pointed out, At present, the nutritional intake of pre-pregnancy and pregnant women in my country is not optimistic.

Although the folic acid supplementation rate of women during pregnancy increased from 20.5% in 2002 to 49.9% in 2009, the proportion of iron and vitamin supplementation was less than 20%, and the lack of micronutrients was still serious.

Relevant data from the "Report on Nutrition and Chronic Disease Status of Chinese Residents (2015)" shows that 17.2% of pregnant women suffer from anemia.

  In this regard, Yu Qi pointed out: "A variety of micronutrients can meet the additional needs of vitamins, minerals and trace elements for women who are preparing for pregnancy, pregnancy and lactation, and effectively prevent women's anemia caused by iron deficiency and folic acid during pregnancy. Not only In this way, nutrients also affect the entire life cycle of women, and peri-pregnancy nutrition will affect the long-term health of the offspring and have an important impact on the life-long disease risk of the offspring."

  In view of this, the "Consensus" recommends that supplementation of a variety of micronutrients containing 0.4mg or 0.8mg of folic acid can effectively reduce the occurrence of neural tube defects. Its effectiveness depends on the frequency and time of supplementation. It is recommended to start daily in the first 3 months of pregnancy. Supplement, to ensure that the threshold concentration for effective prevention of neural tube defects is reached, and to reduce the risk of neural tube defects; supplementation with 0.8mg of folic acid to prevent neural tube defects or more effective, and can effectively prevent congenital heart disease and urinary tract defects Various birth defects such as pyloric stenosis; supplementation of various micronutrients containing folic acid can effectively reduce the concentration of homocysteine ​​in women, thereby reducing pregnancy complications including preeclampsia and pregnancy-induced hypertension, as well as spontaneous abortion and recurrence The risk of miscarriage.

  Let gestation have "preparation" to come

  The intake of a variety of micronutrients also helps to optimize the reproductive environment and increase pregnancy rates.

  "Various micronutrient deficiencies in women with infertility are more common than those in general women, often accompanied by increased homocysteine ​​(Hcy) levels or increased oxidative stress. Supplementing a variety of micronutrients can effectively improve women’s Hcy levels, and It has an antioxidant effect and can reduce the damage of oxidative stress to fertility. Together with the effect of nutrients on the reproductive internal environment, oral supplements can help to improve the outcome of assisted reproduction." Yu Qi pointed out.

  Not only women, reasonable supplementation of nutrients can also improve male infertility.

"Antioxidant therapy is one of the widely used drug treatments for the treatment of male infertility. Because a variety of micronutrients have antioxidant effects, reasonable intake can reduce oxidative stress and improve sperm quality." Yu Qi said.

  For the infertility group, the "Consensus" recommends that: women can reduce the risk of ovulatory infertility by supplementing 0.8mg of folic acid on a daily basis; increase the pregnancy rate within 1 year and reduce the time cost of a successful pregnancy; for men Necessary, reasonable and balanced dietary nutrient intake during the preparation period is an important basis for eugenics; supplementation of nutrients such as zinc may improve male sperm quality through antioxidant effects.

  It is worth mentioning that the offspring of women who adopt assisted reproductive technology may have a higher risk of birth defects.

  The "Consensus" proposes that women with infertility start to supplement a variety of micronutrients before receiving in vitro fertilization-embryo transfer (IVF-ET), which can improve the quality of oocytes and embryos to a certain extent, increase the clinical pregnancy rate and sustained pregnancy Rate, and reduce miscarriage and increase the rate of live births.

Secondly, related studies have shown that supplementing a variety of micronutrients containing 0.8 mg of folic acid can reduce the risk of birth defects such as neural tube defects in the offspring.

  Yu Qi said that the current public's awareness and behavior on the prevention of birth defects still need to be further regulated.

The implementation of this action and the upcoming "Consensus" will provide doctors and the majority of couples of childbearing age with scientific guidance on pre-pregnancy/pregnancy nutrition interventions and healthy behaviors.

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