The Moderna vaccine is the second vaccine approved for use within the European Union.

This vaccine protects you against the disease COVID-19.

You should know this further.

How well does this vaccine protect me against COVID-19?

Moderna's vaccine has a 94 percent effectiveness.

This means that only six in a hundred people who would normally get COVID-19 will still become ill after the vaccination.

The vaccine can well protect the elderly and those at risk for severe COVID-19, such as people with diabetes.

How long does the vaccine work?

The vaccine works well for at least two to three months, according to the Medicines Evaluation Board (MEB).

It is expected that the vaccine will continue to work for a long time afterwards.

We just cannot say this with complete certainty, because there are not yet large groups of people who have received this vaccine more than three months ago.

From what moment does this vaccine work?

The effectiveness of the Moderna vaccine is not 94 percent immediately after one shot.

The vaccine consists of two doses administered 28 days apart.

The effectiveness mentioned above applies from the seventh day after the second dose.

This does not mean that you will not benefit from this vaccine at all until a week after the second dose.

After the first dose, your body will start producing antibodies that can immediately neutralize the corona virus (if you were to catch it).

This will take some time, but the vaccine is expected to partially protect you against COVID-19 about two weeks after the first vaccination.

The protection then improves after the second dose.

See also: Answers to your questions about corona vaccination in the Netherlands

Can you still spread the corona virus after vaccination?

We know how effective this corona vaccine is in preventing disease, but we do not yet know to what extent this vaccine can prevent someone from spreading the coronavirus.

According to Frits Rosendaal, professor of clinical epidemiology at the LUMC, it is almost certain that the approved corona vaccines reduce the chance that you will spread the corona virus.

What are the main side effects?

The table below shows how often common side effects, such as headaches, occurred after vaccination.

These side effects usually occur within two days of vaccination.

Vaccinated individuals generally suffer from it for between one and three days.

There is no evidence that this vaccine causes serious side effects.

What about rare side effects?

Moderna's vaccine was tested on more than 15,000 people before it was approved.

Because of this, we know the common and slightly less common side effects of this vaccine.

The chance of unknown side effects is small, according to the MEB, but not zero.

That is why this vaccine is also further researched after authorization.

Who is this vaccine not suitable for


The Moderna vaccine is approved for use in people over the age of 18.

The reason this vaccine is not approved for children is that this vaccine has not yet been studied in children.

In addition, the vaccine is not recommended for people who are allergic to any of the components of the vaccine.

You can find the ingredients here.

If you are unsure whether you are allergic to any of the ingredients, you can check with your pharmacist or doctor.

The RIVM advises pregnant women to be vaccinated only after their pregnancy.

Little research has been done into the effect of this vaccine on pregnancy.

Animal studies have so far found no indications that the vaccine is unsafe for pregnant women.

The following groups do not necessarily discourage the vaccine, but it is recommended to consult a doctor before vaccination:

  • People taking blood thinners.

  • People who have a poor immune system due to illness or certain medicines.

  • People who have had a severe allergic reaction after vaccination in the past.

There are several reasons why it is recommended to consult a doctor in advance with the above groups.

For example, in people who take blood thinners, it may be necessary to consult with the thrombosis service about when you will be vaccinated.

See also: Two Corona Vaccines Approved: What Are the Differences and Similarities?

How does this vaccine work?

Moderna's vaccine is a so-called mRNA vaccine.

This means that it contains bits of genetic information (mRNA).

This genetic information ensures that a small piece of the corona virus is made in the body.

You cannot get COVID-19 from this piece, but it does train your immune system.

This training ensures that the corona virus can be quickly eliminated if you come into contact with it.

After the pieces of coronavirus have been created, the body quickly breaks down the vaccine.

Contrary to various posts on Facebook and Twitter, these vaccines are unable to change your DNA.

See also: Reader Questions: How Do Pfizer, Moderna and CureVac RNA Vaccines Work?

What if the coronavirus changes?

The coronavirus is constantly changing.

Most of these changes do not affect the effectiveness of corona vaccines, such as that of Moderna.

But it is possible that the vaccine against some (future) variants of the coronavirus is slightly less effective.

Therefore, it is currently being investigated to be sure whether the Moderna vaccine is equally effective in the British and South African variants.

There are no indications yet that the vaccine works less well with these variants.


For example, the corona virus mutated worldwide in the past year

If you are invited to make a vaccination appointment and you have medical questions, for example because you have an immune disorder or a serious allergy, ask your doctor these questions.