Large-scale cohort study results "come out": Survival rates of very preterm infants and very low birth weight preterm infants in China have been significantly improved

  China News Service, August 12 (Reporter Chen Jing) Globally, premature birth is an important cause of death for children and infants under 5 years of age. The reporter learned on the 12th that with the development of Chinese neonatal medicine, the survival rate of very premature infants and very low birth weight premature infants has increased significantly: the overall survival rate of preterm infants with a gestational age of less than 32 weeks is 88%, and the birth weight is less than 1500 grams. The overall survival rate of premature babies is 86%.

Because of the immature development of the body organ system, premature infants can develop many serious diseases such as respiratory distress syndrome, bronchopulmonary dysplasia and retinopathy of prematurity. Photo courtesy of the Pediatric Hospital

  The China Neonatal Collaboration Network and the National Children's Medical Center Neonatal Specialist Alliance released the 2019 annual report, announcing the "China Neonatal Collaboration Network Very Premature Infants/Very Low Birth Weight Infant Cohort" and disclosed the current status of the treatment of premature infants in China. The National Children's Medical Center and the Children's Hospital of Fudan University stated that the results of the cohort study provided true and accurate baseline data for subsequent quality improvement and clinical research.

  It is understood that the cohort study was led by the China Neonatal Network and included 10,823 preterm infants from 57 tertiary hospitals in 25 provinces and municipalities directly under the Central Government into the 2019 statistics. Very preterm infants/very low birth weight infants of this scale The cohort study has not been reported before.

After active treatment, the survival rate of preterm infants with a birth weight of 1000g-1500g is close to the level of developed countries. Photo courtesy of the Pediatric Hospital

  Premature babies are newborns whose gestational age is less than 32 weeks or whose birth weight is less than 1500 grams. Premature infants can develop respiratory distress syndrome, bronchopulmonary dysplasia, sepsis, brain injury, necrotizing enterocolitis and retinopathy of prematurity due to the immature development of the body organ system. According to a cohort study, among preterm infants with a gestational age of less than 32 weeks, 49% were born at 30-31 weeks, and 17% were born at less than 28 weeks; among premature infants with a birth weight of less than 1500 grams, those with a birth weight of less than 1000 grams accounted for 49%. 19%. Among the children enrolled in the cohort study, 79% improved or were cured and discharged.

  It is reported that the Chinese Neonatal Network (CHNN) is a collaborative research network dedicated to neonatal medicine-related research. It aims to establish and operate a standardized database of target populations in the Chinese Neonatal Intensive Care Unit for Chinese and international researchers. Provide platforms and opportunities for high-quality, collaborative clinical research in the field of neonatal/perinatal medicine.

  The collaboration network is chaired by Professor Chen Chao from the Children's Hospital of Fudan University and Professor ShooK Lee from the University of Toronto in Canada. Professor Zhou Wenhao from the Pediatric Hospital of Fudan University and Professor Du Lizhong from the Children's Hospital of Zhejiang University serve as co-chairs. It is understood that the clinical database of the China Neonatal Collaboration Network was officially launched on January 1, 2019. At the same time, a number of high-level multi-center clinical research projects such as "Quality Improvement of China's Neonatal Intensive Care Unit" have been carried out.

  Professor Chen Chao told reporters that as the National Children’s Medical Center, in recent years, the Children’s Hospital of Fudan University has carried out quality improvement studies in the neonatal intensive care units of 25 tertiary hospitals in China through international cooperation to reduce the severity of preterm infants. Disease incidence. The results showed that after active treatment, the survival rate of premature infants with a birth weight of 1000g-1500g is close to the level of developed countries.

  Professor Chen Chao said that the China Neonatal Collaboration Network will be based on the platform of the National Children’s Medical Center and continue to carry out innovative research on clinical epidemiology and disease prognosis with high quality and high credibility through a precise, close and efficient specialist alliance model. Improve the survival rate of premature babies, reduce the incidence of serious diseases, and make China's contribution to the improvement of the level of neonatal/perinatal medical care in China and the world and the improvement of neonatal prognosis. (Finish)