Chinese experts innovate and formulate a "ground-glass nodular" lung cancer diagnosis and treatment strategy to break the general definition and gain international attention
Sino-Singapore Online, June 23 (Chen Jing, Wang Guangzhao, Zhang Yang) For a long time, "ground glass nodules" have puzzled many people. The reporter was informed on the 23rd that Chinese experts have carried out a lot of research on the "ground glass nodular" lung cancer, and took the lead in systematically defining this type of lung cancer as a special clinical subtype, and proposed a classification and treatment strategy for its characteristics.
The team led by Professor Chen Haiquan, director of the Department of Thoracic Surgery of Fudan University Affiliated Tumor Hospital and chief expert of the multidisciplinary comprehensive diagnosis and treatment team for chest tumors, developed the "Fudan Standard" for the diagnosis and treatment of "ground glass nodular" lung cancer. According to reports, Professor Chen Haiquan was invited to write an expert review of the "ground glass nodules" type of lung cancer diagnosis and treatment strategy published in the "Chest Surgery Yearbook", which attracted wide attention. Prior to this, the series of relevant research results have been published in international authoritative journals such as the Journal of Chest Cancer and the Chest Surgery Yearbook.
Studies have confirmed that 95% of lung cancers found in physical examinations are "ground glass nodules" in the image examination report; at the same time, "ground glass nodules" type lung cancer are more and more seen in the "low-risk population of traditional lung cancer" ".
In the research, the team of Professor Chen Haiquan found that there is a significant difference between the "ground-glass nodular" lung cancer and the "cognitive subtype of lung cancer corresponding to pathological diagnosis" in previous cognition. Professor Chen Haiquan believes that some "ground glass" that shows the same characteristics in the imaging report may be completely different subtypes of lung cancer.
This achievement is the first to define ground-glass nodular lung cancer as a special subtype of lung cancer, breaking the previous general definition and laying a foundation for the precise treatment of this type of lung cancer.
Will pleural metastasis affect the survival of patients with ground-glass nodular lung cancer? Professor Chen Haiquan's team further research found that pleural infiltration is not a prognostic factor for mixed ground-glass nodular lung cancer.
Surgery is the main method for the treatment of ground-glass nodular lung cancer. For newly discovered ground-glass nodular lung cancer, Professor Chen Haiquan's team recommends at least 4 to 6 months of follow-up to reduce the proportion of benign patients and avoid overtreatment-benign ground-glass nodular lung cancer usually follows during follow-up disappear. It is reported that the malignant proportion of ground glass nodular lung cancer surgically removed by Professor Chen Haiquan's team accounts for 93%.
At present, in the international field, there is still a lack of consensus on the diagnosis and treatment of multiple-type ground glass nodular lung cancer. Whether the multiple nodules scattered in the lungs are multiple primary lesions or metastases that "run over" from other parts has always been a problem in the field of lung cancer.
Professor Chen Haiquan's team innovatively proposed an imaging-based identification method and gave the identification criteria, that is, multiple ground glass nodules or single solid nodules combined with ground glass nodules should be considered as multiple original hair. Related results were published in the Journal of Oncology Surgery. (Finish)