Symptoms were not known .. Corona virus changes the color of the skin of survivors and affects the brain

Currently, studies are being conducted on the effects of the emerging SARS Cove 2 virus that causes Covid-19 disease, which were unknown, and the most recent effects on the skin and the brain.

And we begin in China, where the skin of two Chinese doctors who had been suffering from the outbreak of Corona Virus Covid-19 has turned unexpectedly dark after their miraculous death.

Writer Billy Thompson said in his report published by the British newspaper Daily Mail that both Dr. Yi Van and 42-year-old Hu Weifeng were infected with the Coruna virus while treating patients at Wuhan Central Hospital in January.

Their supervising doctor told Chinese media that their abnormal skin color was caused by hormonal imbalances, after their liver was damaged by the virus.

Both doctors were diagnosed with infection on January 18, and after being transferred to Wuhan Hospital and then to the Tongyi Hospital Branch, Dr. Yi - the cardiologist - overpowered the virus after delivering it to the artificial respirator or life support device outside the body for 39 days. This device can Compensate the function of the heart and lungs by pumping oxygen to the blood.

The footage, released by Beijing TV station, shows Dr. Zhan Qingyuan of the China-Japan Friendship Hospital speaking to Dr. Yi and Dr. Hu in a ward on April 6 at Tongji Hospital. Dr. Zhan, who lives in Beijing, was treating and examining the duo before he and his team left Wuhan and returned to the capital.

During an interview with Dr. Zhan, Dr. Yi stated that he was recovering well and his wounds had been recovered to a great extent, while Dr. Zhan assured Dr. Ye that he bore the responsibility of "saving his companion."

He was not able to speak at the time because of his poor health, but he shook hands with Dr. Zhan to express his gratitude.

Dr. Li Shuxing, who treated Dr. Hu, suspected that the patients ’skin had become dark due to the type of medication they received at the start of the treatment. He stated that one of the side effects of the drug is the blackening of the skin color, but he did not mention the name of the drug, and Dr. Lee expected that their skin color would return to its normal state after the liver function improved.

The brain and
we move to New York, where doctors treating Covid-19 patients increasingly notice that, in addition to fever, coughing and shortness of breath, other symptoms appear: some patients are so confused that they do not know where they are and what year.

The inability to determine location and time is sometimes associated with hypoxia in the blood, but in some patients the level of confusion appears disproportionate to the level of inflammation in the lungs.

This raises a question about the impact of the emerging corona virus on the brain and nervous system, says Jennifer Frontera, a neurologist at the Langon University Hospital in Brooklyn.

Some studies began describing the phenomenon. In the Journal of the American Medical Association (Gamma), doctors reported that 36% of 214 Chinese patients had neurological symptoms, ranging from loss of smell and nerve pain to seizures and strokes.

In the American medical journal "New England Journal of Medicine", French doctors in Strasbourg said that more than half of the 58 ICU patients were confused or upset, and brain images revealed possible inflammation.

S. said. Andrew Josephson, Head of the Neurology Department at the University of California, San Francisco, told the French news agency: "Everyone says it is a problem with breathing, but it also affects something very valuable to us which is the brain."

"If you feel confused and have trouble thinking, these are good reasons to see a doctor. The old idea that we should only go when we are feeling very distressed is no longer correct," he says.

Viruses and the brain Virologists are
not entirely surprised by the ability of the emerging coronavirus to affect the brain and nervous system, as this association with other viruses, including HIV, has been observed.

Viruses can affect the brain in two main ways, the first by stimulating an abnormal immune response called "cytokine storm", which causes an inflammation of the brain called autoimmune encephalitis, says Michael Toledano, a neurologist at the Mayo Clinic, Minnesota.

The second is through direct infection to the brain or the so-called viral encephalitis. The brain is protected by what is called the blood-brain barrier, and its role is to prevent the penetration of harmful substances into it, but this barrier can be penetrated.

Some make the hypothesis that the nose can be the pathway that connects to the brain, because olfactory loss is common in a large number of Covid-19 patients. However, this has not been verified, and many patients who lose their sense of smell do not have worrisome neurological problems.

The main course is actually the immune response via hyperthermia. To fully verify this, the virus must be detected in the cerebrospinal fluid. This was done once by a 24-year-old Japanese, who was described in the International Journal of Infectious Diseases.

The patient was experiencing confusion and seizures, and images of his brain showed inflammation, but the efficacy of the test has not yet been verified and scientists remain cautious.

"We see a lot of patients are in trouble," he says, adding that this means 40% of the virus's survivors.

It is not known whether these disorders are permanent, as the patient's admission to the recovery room is itself confusing, especially because of the medications given to him.

But a neurologist notes that returning to normal for people with coronavirus appears to be taking longer than those who survived a heart attack or stroke.