[Scientific enough] When "White Plague" meets new crown pneumonia, every sentence they say is worth listening to

CCTV News: March 24, 2020 is the 25th World Tuberculosis Day. Tuberculosis is known as the oldest and most deadly infectious disease in the world, and the tuberculosis known as "white plague" is the most common type of tuberculosis. In most people's minds, tuberculosis (rickets, rickets) is a disease that has been overcome by humans. The reality is that one in four people in the world ’s 7 billion people carry TB bacteria, and 5% -10% of this population may have the opportunity to become TB patients in their lifetime. According to statistics, there are about 10 million new cases each year, and 1.5 million people die of the disease. Tuberculosis is still seriously endangering human health.

Infectious diseases are always lurking around us. They are like bombs that explode at any time and require humans to be vigilant at all times. At present, during the fight against the new crown pneumonia epidemic, I believe that many people have learned lessons from this epidemic, one of which is to not only improve the alertness and timely response to new infectious diseases, but also pay attention to various Harm to humans caused by infectious diseases. What are the differences between tuberculosis and neo-coronary pneumonia? Let's see what happens when "White Plague" meets new crown pneumonia.

I still want to tell you that if you do the tuberculin skin test (TST) or the gamma-interferon release test (IGRAs), you can know if you have been infected with tuberculosis. If you have related symptoms and want to know if you have tuberculosis, you can use sputum smears or sputum culture (4-8 weeks) and molecular biology tests to perform pathogenic tests, and chest imaging Make a diagnosis.

At present, there are three main methods for detecting new coronary pneumonia: nucleic acid reagent detection, viral gene sequencing, serological examination, and of course, combined with chest imaging results to assist diagnosis.

In addition, how to treat the infection is a matter of great concern to everyone. Most patients with tuberculosis will recover after receiving a 6-month cycle of drug treatment. Drug-resistant tuberculosis will require another 18 to 24 months, or even 36 months. According to statistics, the highest cure rate is only 50%. The condition of neocoronary pneumonia is relatively complicated, and the treatment cycle varies from person to person.

Regarding the treatment of tuberculosis, there are effective anti-tuberculosis drugs, but the principles of early, combined, appropriate, regular, and full treatment need to be followed. Current drug development for TB is extremely slow, and it was not until 2016 that the first new anti-TB drug approved in more than 40 years appeared. Once suffering from drug-resistant tuberculosis, according to the latest WHO guidelines, treatment costs need 200,000-300,000 yuan (WHO purchase price), and purchase at market prices or more than 500,000 yuan.

From the current point of view, there is no effective drug for the treatment of neo-pneumocoronary pneumonia, and it is mainly combined treatment with some antiviral drugs, individual Chinese medicine treatment and some symptomatic supportive therapies.

Everyone knows that the first injection of a baby is injected with BCG, but many people do not know its relationship with tuberculosis. BCG can prevent very severe tuberculosis in childhood (such as tuberculous meningitis or systemic disseminated tuberculosis), but it has no protective effect on adults, and there is currently no effective vaccine for adults.

Although scientists from various countries are actively working on research and development, no vaccine is currently available to treat new coronary pneumonia. Therefore, the top priority of the current epidemic prevention and control is "four early": early detection, early reporting, early isolation, and early treatment.

Although infectious diseases are terrible, they are still preventable, controllable and curable. As long as we join hands to fight them together, we will certainly win. Just like this year ’s World Tuberculosis Day, the theme of our propaganda is “joining hands to fight the epidemic, prevent maggots, and protect healthy breathing”. I believe that in the near future, we will definitely overcome tuberculosis and new crown pneumonia. (Planning: Zhang Kezhen Illustration, Design: Shi Tianxin)

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references

1.WHO. Global Tuberculosis Report 2019, WHO / CDS / TB / 2019.15.

2. Ge Junbo and Xu Yongjian. Eighth Edition of Internal Medicine. People's Medical Publishing House, 2013.

3. Guidelines for the implementation of China's tuberculosis control plan (2008 edition). China Union Medical College Press, 2008.

4. Cheng Shiming, Wang Lixia, Chen Wei. Epidemiology of tuberculosis scene. People's Medical Publishing House, 2016.

5. New Coronavirus Pneumonia Prevention and Control Program (Sixth Edition), 2020.

6. New coronavirus pneumonia diagnosis and treatment plan (trial version 7), 2020.

7. Shi Shitong. Two billion people around the world carry TB bacteria. My job is to remove these time bombs. The Gates Foundation, 2019.