The German Brain Foundation said that neurosarcoidosis is granulomas that arise in the nervous system. It can lead to meningitis, facial paralysis, various neurological deficits, and epileptic seizures.

Granulomas in the pituitary gland and hypothalamus can also lead to hormonal disorders such as amenorrhea in women. A doctor should be consulted immediately upon noticing these symptoms to undergo timely treatment. Simple cases are treated with medications containing cortisone, while severe cases are treatment with immunosuppressants.