The US government prepared for a Russian nuclear strike in Ukraine at the end of 2022. US President Joe Biden said that if things continued to develop like this, there would be a risk of using nuclear weapons for the first time since the Cuban Missile Crisis.

A tactical nuclear strike by the Russian armed forces was repeatedly shown to be the West's red line in the Ukraine war. According to the New York Times report, there were diplomatic talks at the highest levels to prevent the risk of a nuclear strike.